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OBJECTIVE Telmisartan, an angiotensin type I receptor blocker (ARB), protects against the progression of atherosclerosis. Here, we investigated the molecular basis of the antiatherosclerotic effects of telmisartan in macrophages and apolipoprotein E-deficient mice. METHODS AND RESULTS In macrophages, telmisartan increased peroxisome proliferator-activated(More)
BACKGROUND Dipeptidyl peptidase-4 (DPP-4) inhibitors modulate incretin hormones and exert anti-diabetic effects in type 2 diabetes mellitus. Treatment with angiotensin II type 1 receptor blockers (ARB) is a proven successful intervention for hypertension with type 2 diabetes. The present study investigated the combined effects of the DPP-4 inhibitor(More)
The male part of the spadix of Dracunculus vulgaris exhibits a degree of temperature regulation by inversely controlled heat production over a 20–35 °C range of tissue temperature. To clarify the effects of temperature on cellular metabolism, comparative analysis was performed using 51 metabolites from two distinct tissues (florets and pith) of thermogenic(More)
In this paper, we propose a design method of the narrow band FIR filter in a Fluency signal space. As a result, we can make superior narrow band FIR filters than ordinary one. While an FIR filter has advantages that it is stable and can realize perfect linear phase, its transfer function can be of higher order according to desired accuracy. One of such(More)
BACKGROUND The induction of heat shock protein (HSP) 72 by mild electrical stimulation with heat shock (MES + HS), which improves visceral adiposity and insulin resistance in mice, may be beneficial in treating metabolic syndrome (MS) or type 2 diabetes mellitus (T2DM). METHODS Using open-label crossover trials, 40 subjects with MS or T2DM were randomly(More)
—In this paper, we consider to formulate an image data hiding scheme based on error diffusion. By using the scheme, visual patterns are embedded in a halftone image without affecting its perceptual quality depending on a halftone key image. The scheme has the feature of visual cryptography with respect to extracting of the embedded patterns, i.e., when we(More)
The induction of beige adipogenesis within white adipose tissue, known as "browning", has received attention as a novel potential anti-obesity strategy. The expression of some characteristic genes including PR domain containing 16 is induced during the browning process. Although acetate has been reported to suppress weight gain in both rodents and humans,(More)
Recently, various ways to reduce the size of multimedia data have been developed. However, there is a problem of the tradeoff of data size, and quality. In compressed audio encoding, high frequency components are lost from the original signal. It is impossible to retrieve the frequency components that have been cut using the conventional interpolation(More)
We study formulating the ubiquitous cloud (UC) model proposed by Murakami at KDDI [4]. Based on the analysis for Ad Hoc wireless network by Gupta and Kumar [3], we rearrange their setting to an appropriate one for the UC, and then give an evaluation of network capacity called transport capacity. The evaluation takes the form similar to [3], when(More)
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