Shuhai Li

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BACKGROUND The aim of this study was to examine BRF2 expression in patients with non-small cell lung cancer (NSCLC) and explore the relationship of BRF2 protein with clinicopathologic factors, tumor angiogenesis and prognosis. METHODS Both BRF2 protein and intratumoral microvessels were examined by immunohistochemical staining in 107 non-small cell lung(More)
Human mesenchymal stem cells (hMSCs) are mostly studied for their potential clinical use. Recently, much attention in the field of cancer research has been paid to hMSCs. In this study, we investigated the influence of hMSCs on the proliferation of lung cancer cell lines SK-MES-1 and A549 in vitro and in vivo by using a co-culture system and the(More)
The objective of this study was to identify the effects of exogenous putrescine on photosynthetic performance and heat dissipation capacity in cucumber seedlings under salt stress. The stress of 75 mM NaCl for 7 days caused a significant decrease in net photosynthetic rate (P N ). The experiment employed a chlorophyll fluorescence imaging technique and(More)
This study focuses on the impact of carbohydrate metabolism and endogenous polyamines levels in leaves of cucumber seedlings under salt stress by exogenous BRs. The effects of 24-epibrassinolide (EBL) on carbohydrate metabolism and endogenous content of polyamines were investigated in cucumber seedlings (Cucumis sativus L. cv. Jinyou No. 4) exposed to(More)
In this study, we found that increased BRF2 protein expression was prevalent in NSCLC. Overexpression of BRF2 correlated with abnormal expression of E-cadherin, N-cadherin, and snail. Additionally, expression of BRF2 was found to be an independent prognostic factor in NSCLC patients. Furthermore, we showed that targeted knockdown of BRF2 expression could(More)
This paper considers two additional factors of the widely researched vehicle routing problem with time windows VRPTW. The two factors, which are very common characteristics in realworld, are uncertain number of vehicles and simultaneous delivery and pickup service. Using minimization of the total transport costs as the objective of the extension VRPTW, a(More)
Based on previous findings regarding the angiogenic activities and prognostic roles of metastasis‑associated protein 1 (MTA1) in early‑stage non‑small cell lung cancer, the clinicopathological and prognostic significance of MTA1 protein expression, and its correlation with angiogenesis in lung invasive adenocarcinoma, were further assessed in the present(More)
The apoptotic ligand TNF-related apoptosis-inducing ligand (TRAIL) is believed to be a promising candidate for cancer gene therapy, yet gene therapy strategies to tackle this disease systemically are often impaired by inefficient delivery of the vector to the tumor tissue. Mesenchymal stem cells (MSCs) have been shown to home to tumor sites and could(More)
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