Shufeng Zhou

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Thiopurine methyltransferase (TPMT) catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine (6-MP), thioguanine and azathioprine (AZA). These drugs are used to treat conditions such as acute lymphoblastic leukemia, inflammatory bowel disease, rheumatoid arthritis, and organ transplant rejection. This review highlights the polymorphisms of(More)
There are a lot of difficulties in the ontology generation from relational database such as unclear generation approaches, un-unified ontology languages and so on. So in order to provide unified ontology and improve the quality of ontology generation, approach proposed in this paper firstly extracts database metadata information from relational database(More)
Ontologies play an important role in solving the problem of semantic heterogeneity of heterogeneous data sources. The ontology acquisition from the relational database is one of the fundamental technologies on the information integration field. Ontology acquisition from relational database (OARDB) and transformation rules used are presented and discussed.(More)
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