Shudong Zhou

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BACKGROUND AND OBJECTIVE Several antiviral therapies are now available for patients with chronic hepatitis B (CHB), but the most cost-effective strategy for Chinese patients is unclear. The aim of this study was to estimate the long-term cost effectiveness of the antiviral treatments (lamivudine, adefovir, telbivudine and entecavir) for hepatitis B e(More)
OBJECTIVE Tenofovir (TDF) and entecavir (ETV) are both potent antiviral agents for the treatment of chronic hepatitis B virus (HBV) infection. Multiple studies have compared efficacy and safety of these two agents, but yielded inconsistent results. Hence, we conducted a meta-analysis to discern comparative efficacy and safety. METHODS Published data(More)
Long non-coding RNAs (lncRNAs) have been shown to play critical regulatory roles in diverse biological processes in plants. However, the presence of lncRNAs and their potential functions in hot pepper are still unknown. Using strand-specific RNA-sequencing, a total of 2505 putative lncRNAs were identified in the fruits of hot pepper. The lncRNAs were(More)
MicroRNAs (miRNAs) are non-coding small RNAs which play an important regulatory role in various biological processes. Previous studies have reported that miRNAs are involved in fruit development in model plants. However, the miRNAs related to fruit development and quality in hot pepper (Capsicum annuum L.) remains unknown. In this study, small RNA(More)
BACKGROUND According to the partial smoke-free legislation implemented on 1 September 2010 in Guangzhou, China, smoke-free did not cover all indoor areas. Some places have a full smoking ban (100 % smoke-free), other places have a partial smoking ban, and homes have no ban. This study aimed to compare the smoking behaviors before and after implementation of(More)
INTRODUCTION To explore the improvement of clinical symptoms after treatment on patients to explore the improvement of clinical symptoms after treatment on patients with depression under the latent growth curve modeling. 514 patients were studied with Hamilton with depression under the latent growth curve modeling. 514 patients were studied with Hamilton(More)
We have observed 23 Class 0 sources in the HCO J = 4 − 3 and 3 − 2 lines. The mean bolometric temperature of the 16 sources with well-determined values is 44 K and the mean luminosity is 5.7 L⊙, excluding two sources of considerably higher luminosity. Nine sources, including three sources previously suggested to be collapsing, have the correct (blue)(More)
BACKGROUND Tenofovir disoproxil fumarate (TDF) is newly available for treatment of chronic hepatitis B patients in China. To date, no study has been conducted to examine the cost-effectiveness of this treatment. The aim of this study was to estimate the cost-effectiveness of TDF versus four oral nucleos(t)ide analogs [lamivudine (LAM), adefovir (ADV),(More)
To compare two commonly used statistical approaches:the multilevel model and the latent growth curve model in analyzing longitudinal data. A longitudinal data set, obtained from the quality of life in patients with colorectal cancer after operation, was used to illustrate the similarities and differences between the two methods. Results from the study(More)
BACKGROUND In the X-ray repair cross-complementing group 1 (XRCC1) gene, a polymorphism, Arg399Gln (rs25487), has been shown to change neoconservative amino acid and thus result in alternation of DNA repair capacity. Numerous studies have investigated the association between Arg399Gln and breast cancer risk in the American population, but yielding(More)