Shucheng Zhang

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AIM In this study, we aimed to establish a mouse model of repeated medical termination of pregnancy in order to determine subsequent outcomes. METHODS A model of mifepristone (RU 486)-induced medical abortion was established in BALB/c mice to facilitate the investigation of the impact of medical abortion on subsequent pregnancies, including litter sizes(More)
STUDY QUESTION How is vascular endothelial growth factor (VEGF) expression regulated by hypoxia inducible factor 1 alpha (HIF1A) during menstruation? SUMMARY ANSWER After progesterone (P4) withdrawal, HIF1A was activated and it directly up-regulated VEGF mRNA expression and this regulation was the highest during endometrium breakdown in the mouse(More)
This study examines the production data of dou in a controlled elici-tation task performed by English-speaking learners of Chinese. The results show that post-intermediate learners produced dou at a similar rate regardless of the type of NP that is intended to be quantified by dou, which indicates that learners in this group have not fully acquired or(More)
BACKGROUND To explore the molecular basis of the different ultrasonic patterns of the human endometrium, and the molecular marker basis of local injury. METHODOLOGY/PRINCIPAL FINDINGS The mRNA and protein expression of FKBP52, progesterone receptor A (PRA), progesterone receptor B (PRB), and HB-EGF were detected in different patterns of the endometrium by(More)
Neuroinflammation plays an important role in vascular dementia(VD). Our previous work showed that mammalian Ste20-like kinase 1 (MST1) and the gene for a downstream transcription factor, FOXO3, play major roles in lipopolysaccharide (LPS)-induced apoptosis in hippocampal neurons. The neurotoxic effects of LPS are derived from its ability to cause an(More)
OBJECTIVE This study aimed to assess the trend of human fecundity over time in China. METHODS This retrospective study was conducted in Tongliao, China. Couples who were married during the time period between January 1, 1981 and December 31, 2003 were considered eligible for this study. A total of 27,413 individuals provided valid information via(More)
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