Shucheng An

Learn More
High levels of paternal care are important for the development of social behavior in monogamous rodents. However, the effects of paternal care on the formation of pair bonding and underlying neuroendocrine mechanisms, especially the involvements of dopamine system and corticosterone, are not well understood. We investigated effects of paternal deprivation(More)
This study examined whether neonatal paternal deprivation (PD: father was removed and pups were raised just by mother) or early deprivation (ED: pups were raised by both parents except separated from not only the dam but also the peers for three hours a day from PND 0 to 13) has long-term effects on anxiety and social behaviors of adult mandarin voles.(More)
Previous studies on parental behavior have primarily focused on maternal behavior, with little research directed at observing paternal behavior. The effects of neonatal paternal deprivation and early deprivation on adult parental behavior and estrogen receptor α (ERα) especially remain unclear. This study examined whether paternal deprivation or early(More)
The characteristics of baroreceptor firing patterns were recognized in experiment, and their dynamics revealed in theoretical analysis. During blood pressure elevation, baroreceptors gradually exhibited bursting, continuous firing, and paradoxical bursting patterns. The bursting was generated through the repeated bifurcations between rest and spiking, the(More)
Neonatal manipulation of oxytocin (OT) has long-term effects on behavior and physiology. The objective of this research was to determine if neonatal exposure to OT can affect partner preferences and to characterize the mechanisms underlying social behavior such as neural activities of relevant brain regions in socially monogamous mandarin voles (Microtus(More)
Early deprivation is popularly used in rodent models as an early life social stress to investigate and determine the factors that affect the development of the brain and behavior. Ultrasonic calls made by pups play an important role in parental-pup interactions during the neonatal period. However, whether repeated early deprivation affects the properties of(More)
Many receptors, including thermal receptors and mechanical receptors, are only activated by stimuli within a clearly defined range of intensities. Differences in the receptive ranges enable individual receptors and their sensory centers to precisely detect the intensity of the stimulus and changes in intensity. Baroreceptors are the sensory terminals of the(More)
Repetin (RPTN) protein is a member of S100 family and is known to be expressed in the normal epidermis. Here we show that RPTN is ubiquitously expressed in both mouse and human brain, with relatively high levels in choroid plexus, hippocampus and prefrontal cortex. To investigate the expression of RPTN in neuropsychiatric disorders, we determined serum(More)
Early life stress has a long-term negative impact on emotion, learning, memory and adult sexual behavior, and these deficits most likely impair pair bonding. Here, we investigated whether early social deprivation (ED) affects the formation of pair bonds in socially monogamous mandarin voles (Microtus mandarinus). In a partner preference test (PPT),(More)
  • 1