Shubhra Gangopadhyay

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We have developed and tested transparent microelectrode arrays capable of simultaneous amperometric measurement of oxidizable molecules and fluorescence imaging through the electrodes. Surface patterned microelectrodes were fabricated from three different conducting materials: Indium-tin-oxide (ITO), nitrogen-doped diamond-like carbon (DLC) deposited on top(More)
 We describe a three-course introductory sequence in fluorescence-based microanalytical systems. The series is aimed at beginning graduate students and advanced undergraduates who have an interest in MEMS and microelectronics. The first course is introductory with the objective of educating students in the basics of silicon microfabrication. Devices are(More)
Here we describe a method to fabricate a multi-channel high-throughput microchip device for measurement of quantal transmitter release from individual cells. Instead of bringing carbon-fiber electrodes to cells, the device uses a surface chemistry approach to bring cells to an array of electrochemical microelectrodes. The microelectrodes are small and(More)
Photorelease of caged Ca(2+) is a uniquely powerful tool to study the dynamics of Ca(2+)-triggered exocytosis from individual cells. Using photolithography and other microfabrication techniques, we have developed transparent microchip devices to enable photorelease of caged Ca(2+), together with electrochemical detection of quantal catecholamine secretion(More)
ACKNOWLEDGEIVIENTS I would like to thank my thesis advisor Drs. Shubhra Gangopadhyay and Jordan Berg for their support, encouragement and valuable guidance throughout this work. I would not have been able to finish this work without their guidance and moral support. I am grateful to Dr. Gangopadhyay, La Pierre Chair Professor at the University of Missouri(More)
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract We introduce nanogap-embedded silver plasmonic gratings for single-molecule (SM) visualization using an epifluorescence microscope. This silver plasmonic plat‐ form was fabricated by a cost-effective nano-imprint lithography(More)
We report metal/p-Si contact barrier modification through the introduction of either "isolated" or "nonisolated" tilted-target-sputtered sub-2 nm platinum nanoparticles (Pt NPs) in combination with either a 0.98 nm Atomic Layer Deposited Al2O3 or a 1.6 nm chemically grown SiO2 dielectric layer, or both. Here, we study the role of these Pt NP's size(More)
In this paper, we present a vision for a medical cyber physical system that interacts with the human body for continuous, personalized health monitoring. Internal and external parameters, including health history and environmental factors would be considered in the personalized measurement control process. Here, we discuss dehydration monitoring as one(More)