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BACKGROUND Small RNA-mediated gene silencing plays evolutionarily conserved roles in gene regulation and defense against invasive nucleic acids. Virus-derived small interfering RNAs (vsiRNAs) are one of the key elements involved in RNA silencing-based antiviral activities in plant and insect. vsiRNAs produced after viruses infecting hosts from a single(More)
BACKGROUND Various etiologies that contribute to the loss of pregnancy have been proposed. Despite the lack of established and uniform screening methods for recurrent pregnancy loss (RPL), there are several factors considered to be definite (or probable) causes of RPL. Data describing the etiological characteristics of RPL consist almost entirely of(More)
A fully automated microextraction by packed sorbents (MEPS) coupled with large volume injection gas chromatography-mass spectrometry (GC-MS) has been developed for the determination of eight polycyclic aromatic hydrocarbons (PAHs) in environmental water samples. Naphthalene (Nap), pyrene (Pyr), anthracene, acenaphthylene, phenanthrene, fluoranthene (Flr),(More)
OBJECTIVES To assess the elastic properties of the normal Achilles tendon in different age groups by Virtual Touch imaging quantification (VTIQ; Siemens Medical Solutions, Malvern, PA) shear wave elastography. METHODS A total of 326 healthy volunteers older than 18 years were divided into different groups by sex and age. The thickness, shear wave velocity(More)
The aim of this study was to evaluate the value of core needle biopsy (CNB) in the diagnosis of sonographically suspicious thyroid nodules. We retrospectively reviewed 997 patients with sonographically suspicious thyroid nodules who underwent CNB using pathological results as gold standard. In our result, the accuracy of CNB was 98.0%, and its area under(More)
Taxol (paclitaxel) is a diterpenoid compound with significant and extensive applications in the treatment of cancer. The production of Taxol and relevant intermediates by engineered microbes is an attractive alternative to the semichemical synthesis of Taxol. In this study, based on a previously developed platform, the authors first established taxadiene(More)
Forkhead box M1 (FoxM1) transcription factor is related to the pathogenesis of various malignancies and recent evidence indicates that FoxM1 promotes epithelial-mesenchymal transition (EMT) in breast cancer. Metformin can inhibit the progression of cancer. However, whether FoxM1 plays a role in EMT in prostate cancer (PCa) and whether metformin can suppress(More)