Shu-hua Cao

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OBJECTIVE To examine the efficacy of a treatment regimen combining modern (Western) medication and a traditional Chinese medicinal recipe Modified Liang-Ge San on sepsis, and its effect on platelet parameters/activation, platelet TLR4 expression and the intensity of inflammatory response in the patients. METHODS 64 patients with sepsis were randomly(More)
OBJECTIVE To observe the value of nuclear factor-KappaB(NF-KappaB) and I Kappa B mRNA expression estimation on determining the prognosis of patients with multiple organ dysfunction syndrome (MODS). METHODS Forty-three MODS patients were divided into two groups based on their prognosis: the survivor group (n =28) and the non-survivor group (n=15). Another(More)
OBJECTIVE To observe the therapeutic effect of Shennong No. 33 (SN33) in treating multiple organ dysfunction syndrome (MODS) by APACHE II and APACHE II scoring. METHODS One hundred and twenty-nine patients of MODS were randomly divided into the treated group (n = 72) and the control group (n = 57), they were treated with comprehensive therapy and to the(More)
OBJECTIVE To observe whether the membrane attack complex C5b-9 would accumulate in the rats' liver after receiving the assault of traumatic hemorrhagic shock, and whether the membrane attack complex deals an impact on liver apoptosis. METHODS Fifty male healthy Wistar rats were randomly divided into five groups: normal group, 1, 3, 6, 24 hour model(More)
OBJECTIVE To observe the effects of Modified Liangge Powder (MLP) on the expressions of platelet toll like receptor 4 (TLR4) and the release of platelet-derived cytokines interleukin 8 (IL-8), beta platelet globulin (beta-TG), soluble CD40 ligand (sCD40L). METHODS The modulating effects on the release of cytokines from mice platelets by TLR4 ligand(More)
OBJECTIVE To observe the influence of propofol on corticosteroid, and cytokines in rats after hemorrhagic shock and resuscitation, as well as its protective effects on vital organs. METHODS Sixty-six male Wistar rats were randomly divided into three groups: control group, hemorrhagic shock and resuscitation group and propofol treatment group. After the(More)
BACKGROUND Infection-induced thrombocytopenia (TCP) is an independent risk factor for death of patients with sepsis, but its mechanism is unknown. This study aimed to explore the underlying mechanism of TCP based on the relationship between TLR4 expression and platelet activation in septic patients. METHODS A total of 64 patients with sepsis were(More)
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