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Macular Structures, Optical Components, and Visual Acuity in Preschool Children after Intravitreal Bevacizumab or Laser Treatment.
Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model.
Gain of Slug expression, filopodium formation and stem-like properties in metastatic HNSCC cells are demonstrated, rendering this model a powerful tool for the development of diagnostic biomarkers and identification of therapeutic targets for H NSCC.
Imiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell line.
Imiquimod-induced ROS production disrupts the balance of mitochondrial dynamics and increases mitophagy in skin cancer cells.
Hydroquinone-salicylic acid conjugates as novel anti-melasma actives show superior skin targeting compared to the parent drugs.
Recent Advances Using Phosphodiesterase 4 (PDE4) Inhibitors to Treat Inflammatory Disorders: Animal and Clinical Studies
Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells.
Chronic Iron Overload Results in Impaired Bacterial Killing of THP-1 Derived Macrophage through the Inhibition of Lysosomal Acidification
Findings may explain the impaired innate immunity of thalassemic patients with chronic iron overload, suggesting the manipulation of lysosomal function as a novel therapeutic approach.
Anti-PDGF receptor β antibody-conjugated squarticles loaded with minoxidil for alopecia treatment by targeting hair follicles and dermal papilla cells.
Real-World Effectiveness of Adjuvant Oxaliplatin Chemotherapy in Stage III Colon Cancer: A Controlled Interrupted Time Series Analysis
Among real-world patients with stage III colon cancer, the introduction of oxaliplatin does not yield a significant improvement in survival, and future work should identify the subpopulation(s) of patients who benefit significantly from the addition of oxaloplatin.