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AIM To investigate psychopathology in children with neurofibromatosis type 1 (NF1), particularly the prevalence of autism spectrum disorder (ASD) and attention-deficit-hyperactivity disorder (ADHD) symptomatology, using a population-based sampling approach. METHOD Standard questionnaire screen reports were analysed for ASD (Social Responsiveness Scale,(More)
Importance Recent reports have demonstrated a higher incidence of autism spectrum disorder (ASD) and substantially elevated autistic trait burden in individuals with neurofibromatosis type 1 (NF1). However, important discrepancies regarding the distribution of autistic traits, sex predominance, and association between ASD symptoms and attentional problems(More)
Neurofibromatosis Type 1 (NF1) is a common autosomal dominant single-gene disorder, in which the co-occurrence of autism spectrum disorder (ASD) has attracted considerable research interest recently with prevalence estimates of 21-40%. However, detailed characterization of the ASD behavioral phenotype in NF1 is still lacking. This study characterized the(More)
In this paper, a region level based image fusion technique, using wavelet transform, has been implemented and analyzed. The proposed methodology considers regions as the basic feature for representing images and uses region properties for extracting the information from them. A segmentation algorithm is proposed for extracting the regions in an effective(More)
Studies examining the application of information technology to the delivery of health-care services often highlight the anticipated benefits. In consequence, the benefits of health-care information technology adoption, often referred to as 'e-health', are widely reported yet there is limited empirical evidence as to how such benefits can be realized. Design(More)
AIMS AND METHODS The aim of this survey was to explore staff attitudes to the indoor smoking ban in a medium secure unit and to ascertain if they had experienced any difficulties in imposing the ban in the four months after its introduction. All staff members available on duty who agreed to participate in the survey were interviewed using a semi-structured(More)
The large numbers of images has posed increasing challenges to computer systems to store and manage data effectively and efficiently. This paper implements a CBIR system using different feature of images through four different methods, two were based on analysis of color feature and other two were based on analysis of combined color and texture feature(More)
Noma is a gangrenous disease of the orofacial region that leads to severe facial tissue destruction and is a significant cause of death among children. With the advent of modern antibiotics and improved nutrition, children with noma may survive into adulthood, but must face the challenge of undergoing repair of the sequelae of noma. This report describes a(More)
BACKGROUND The prevalence of antidepressant prescribing in children and adolescents increased steadily in the United States and parts of Europe between 2005 and 2012 despite regulatory safety warnings. Little is known about the characteristics of those being prescribed antidepressants for the first time. METHODS A longitudinal study of antidepressant(More)
A stable and effective industrial relations system is vital for the economic and social development of any country. It is on this foundation that sustained economic growth with equitable distribution of income, especially to labour, can be achieved. In turn, collective bargaining, which is an integral component of industrial relations, is essential if(More)