Shreya Mandal

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The total antioxidative activity of L. ingluviei ADK10 isolated from chicken intestine intact cells and cell free culture supernatant (CFCS) was 54- 67.95%. The ability to scavenge a,a-Diphenyl-b-Picrylhydrazyl free radical ranged from 71 and 64% in intact cells and CFCS respectively. Total reducing activity of bacteria was equivalent to 290 microM/L of(More)
OBJECTIVE To investigate phytochemical screening, antimicrobial activity and qualitative thin layer chromatographic separation of flavonoid components, antioxidant activity and total flavonoid compound of Terminalia arjuna. METHODS For phytochemical screening, some common and available standard tests were done. Antimicrobial bioassay was done through agar(More)
Uremia means excess nitrogenous waste products in the blood & their toxic effects. An acute acetaminophen (paracetamol, N-acetyl p-aminophenol; APAP) overdose may result into potentially fatal hepatic and renal necrosis in humans and experimental animals. The aims of this present study were to investigate the protective effect of alpha-lipoic acid (ALA) on(More)
In the present study, Lactobacillus ingluviei ADK10 (Acc. No. JQ395039) from intestinal origin was tested for its probiotic characteristic as well as uremia ameliorating activity on acetaminophen induced uremic rats. The results revealed that L. ingluviei ADK10 was able to tolerate pH 3.0–9.0 and 0.5% bile salt along with good hydrophobicity (67%) and(More)
Currently kidney disease appears a foremost problem across the world. Acetaminophen is a commonly used antipyretic agent, which in high doses, causes uremia and used for experimentally induction of kidney disease. Bacteriotherapy affords a promising approach to mitigate uremic toxins by ingestion of urease positive bacteria, probiotics and symbiotic able to(More)
Uremia is a major feature of chronic kidney diseases (CKD). Studies were conducted with a standard urease producing probiotic strain, Streptococcus thermophilus (MTCC 1938) to explore the effectiveness of probiotic organism against uremia. The therapeutic potential of the probiotic bacterium was tested against acetaminophen (APAP) induced uremic rats.(More)
The gastrointestinal tract of the human and other mammals is populated by a vast and diverse group of microbes in a composite manner (Frank and Pace, 2008; Ito, 2005). Bacteria are the major population of the alimentary tract and this native microflora is commonly designated the gut microflora (Ito, 2005). Microbial flora present in the microenvironment of(More)
ARTICLE INFO ABSTRACT Article history Received 12 August 2016 Accepted 3 September 2016 Uremia, acute kidney injury (AKI), chronic kidney disease (CKD) and end-stage renal disease (ESRD) have become worldwide public health problems. There are many causes for acute renal failure which mainly includes acute tubular necrosis which occurs either due to ischemia(More)
Background: Curd is an important fermented food which is generally consumed by the community people in large scale and becomes a functional upon incorporating probiotics-live microorganisms due to a great variety of positive health effects. Methods: In this study, pure cultures of Lactobacillus casei (MTCC1408), L fermentum (MTCC 903), L rhamnosus(More)
Now days, herbal medicines are widely used to treat, manage and cure the kidney diseases as well as reduce uremia, acute nephritis & nephritic syndrome. The present study was to evaluate the antiuremic and antioxidative effect of Asparagus racemosus (AR) on acetaminophen induced uremic male rats. The study was designed with 36 male albino rats which were(More)
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