Shoko Ikema

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Sexual precocity results from both GnRH-dependent and GnRH-independent mechanisms. The GnRH-dependent forms of precocious puberty can be treated effectively with long-acting agonist analogues of GnRH. However, for some children who have a poor growth rate during the analogue therapy, an additional growth hormone therapy should be considered to get them near(More)
SummaryA newborn girl is reported with seemingly typical Apert syndrome with preaxial polysyndactyly of the feet. As a result of reevaluation of familial cases of acrocephalosyndactyly with polysyndactyly, acrocephalosyndactyly is suggested to be divided into two major groups. Apert-Pfeiffer type (acrocephalosyndactyly type I) is characterized by(More)
Hypercalciuria is a common side effect during total parenteral nutrition (TPN). We report a patient with long-term TPN, who demonstrated hypercalciuria, hypercalcemia and growth retardation. The patient is a six-year-old Japanese girl with Hirschsprung disease (jejunal agangliosis). Jejunostomy was performed at one-month old and since then her nutrition has(More)
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