Shoichi A. Shimamoto

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In Parkinson's disease (PD), striatal dopamine denervation results in a cascade of abnormalities in the single-unit activity of downstream basal ganglia nuclei that include increased firing rate,(More)
OBJECTIVE To develop a reliable software method using a topographic analysis of time-frequency plots to distinguish ripple (80-200 Hz) oscillations that are often associated with EEG sharp waves or(More)
Shoichi A. Shimamoto,1* Elena S. Ryapolova-Webb,1* Jill L. Ostrem,2 Nicholas B. Galifianakis,2,3 Kai J. Miller,4 and Philip A. Starr1,3 Departments of 1Neurological Surgery and 2Neurology, University(More)
The presence of high frequency discharge neurons with long periods of silence or "pauses" in the globus pallidus pars externa (GPe) is a unique identifying feature of this nucleus. Prior studies have(More)
OBJECTIVE To develop and validate a detector that identifies ripple (80-200 Hz) events in intracranial EEG (iEEG) recordings in a referential montage and utilizes independent component analysis (ICA)(More)