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We demonstrate a novel application of TiO2 photocatalysis for modifying the cell affinity of a scaffold surface in a cell-culture environment. An as-deposited octadecyltrichlorosilane self-assembled monolayer (OTS SAM) on TiO2 was found to be hydrophobic and stably adsorbed serum albumins that blocked subsequent adsorption of other proteins and cells. Upon(More)
Organic contaminants adsorbed on the surface of titanium dioxide (TiO2) can be decomposed by photocatalysis under ultraviolet (UV) light. Here we describe a novel protocol employing the TiO2 photocatalysis to locally alter cell affinity of the substrate surface. For this experiment, a thin TiO2 film was sputter-coated on a glass coverslip, and the TiO2(More)
There are several indications that brain is organized not on a basis of individual unreliable neurons, but on a micro-circuital scale providing Lego blocks employed to create complex architectures. At such an intermediate scale, the firing activity in the microcircuits is governed by collective effects emerging by the background noise soliciting spontaneous(More)
Excitatory and inhibitory neurons have distinct roles in cortical dynamics. Here we present a novel method for identifying inhibitory GABAergic neurons from non-GABAergic neurons, which are mostly excitatory glutamatergic neurons, in primary cortical cultures. This was achieved using an asymmetrically designed micropattern that directs an axonal process to(More)
Takashi Tanii, Sho Kono, Kohei Sekine, Koji Ishihara, Soya Fujimori, Kazuki Noda, Hideaki Yamamoto 1 Department of Electronic and Physical Systems, 2 Department of Nanoscience and Nanoengineering, Waseda University, 3-4-1 Okubo, Shinjuku, Tokyo 169-8555, Japan. 3 Frontier Research Institute for Interdisciplinary Sciences, Tohoku University, 6-3(More)
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