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— This paper is concerned with the problem of robust control for a class of uncertain stochastic systems with discrete and distributed time-varying delays via dynamic output feedback control. The parameter uncertainties of system matrices are assumed to be norm-bounded. The purpose is to design a dynamic output feedback controller such that the closed-loop(More)
BACKGROUND Microglial activation plays an important role in neurodegenerative diseases through production of nitric oxide (NO) and several pro-inflammatory cytokines. Lipoxins (LXs) and aspirin-triggered LXs (ATLs) are considered to act as 'braking signals' in inflammation. In the present study, we investigated the effect of aspirin-triggered LXA4 (ATL) on(More)
Microglia play key roles in innate immunity, homeostasis, and neurotropic support in the central nervous system. Similar to macrophages, microglia adopt two different activation phenotypes, the classical and alternative activation. Resolvin D1 (RvD1) is considered to display potent anti-inflammatory and pro-resolving actions in inflammatory models. In this(More)
— This paper deals with the consensus control of a multi-agent system with state and measurement disturbances, and proposes a distributed dynamic output feedback protocol. By defining an appropriate controlled output, the consensus control problem is reformulated as an H ∞ control problem. Using H ∞ techniques, a sufficient condition in terms of linear(More)
INTRODUCTION Fungal infection is increasingly common in critical illness with severe sepsis, but the influence of invasive fungal infection (IFI) on severe sepsis is not well understood. The aim of this study was to investigate the impact that IFI has on the outcomes of critically ill surgical patients with severe sepsis in China by means of matched cohort(More)
— This paper considers the flocking of a class of multi-agent systems with switching topology in a noisy environment. We have shown that although the information is contaminated by variable noises, all agents can form and maintain flocking if the gradient of the environment is bounded and the interaction graphs are jointly connected. The proposed results(More)
(−)-Epigallocatechin-3‑gallate (EGCG), the predominant constituent of green tea, has been demonstrated to be neuroprotective against acute ischemic stroke. However, the long-term actions of EGCG on neurogenesis and functional recovery after ischemic stroke have not been identified. In this study, C57BL/6 mice underwent middle cerebral artery occlusion (60(More)
Hyperforin, the main active ingredient of the medicinal plant Hypericum perforatum, has been shown to be neuroprotective against acute ischemic stroke. However, the long-term actions of hyperforin on the post-stroke functional recovery and underlying mechanisms have not been investigated. C57BL/6 wild-type mice or interleukin (IL)-17A knock-out mice(More)
BACKGROUND Early goal-directed therapy (EGDT) is used to reduce mortality from septic shock and could be used in early fluid resuscitation of acute respiratory distress syndrome (ARDS). The aim of the present study was to assess the effects of restrictive (RFR) and nonrestrictive fluid resuscitation (NRFR) on hemodynamics, oxygenation, pulmonary function,(More)