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The present study investigated whether the human brain is sensitive to valence differences in emotionally negative stimuli by recording event-related potentials (ERPs) for extremely negative (EN), moderately negative (MN), and neutral pictures while subjects perform a standard/deviant categorization task, irrespective of the emotional valence of the(More)
Previous studies have revealed that personal responsibility has an influence on outcome evaluation, although the way this influence works is still unclear. This study imitated the phenomenon of responsibility diffusion in a laboratory to examine the influence of the effect of responsibility diffusion on the processing of outcome evaluation using the(More)
The pre-attentive processing of Cantonese tones was studied with an auditory passive oddball paradigm. Event-related potentials to standard and deviant auditory stimuli were recorded as participants watched a silent movie attentively. The standards and deviants differed in either pitch level or pitch contour. Mismatch negativity (MMN) and P3a were elicited(More)
The feedback-related negativity (FRN) in brain potentials is typically observed for the outcome evaluation concerning one's performance or monetary reward. Using a task in which the participant guesses whether the first stimulus (S1) would have the same color as the subsequently presented second stimulus (S2), this study demonstrates that the FRN to S2,(More)
Feedback-related negativity (FRN) is sensitive to both monetary loss and evaluation of the correctness of a response. This study used a gambling task that required participants to choose between two cards that were unpredictably associated with monetary gains or losses. Feedback stimuli then indicated gain or loss, and the correctness of the participant's(More)
Excessive bone resorption by osteoclasts within inflamed joints is the most specific hallmark of rheumatoid arthritis. A. flaccida has long been used for the treatment of arthritis in folk medicine of China; however, the active ingredients responsible for the anti-arthritis effects of A. flaccida are still elusive. In this study, W3, a saponin isolated from(More)
Using the event-related optical signal (EROS) technique, this study investigated the dynamics of semantic brain activation during sentence comprehension. Participants read sentences constituent-by-constituent and made a semantic judgment at the end of each sentence. The EROSs were recorded simultaneously with ERPs and time-locked to expected or unexpected(More)
Both behavioral and neurophysiological evidence shows the advantage of object visualizers in object-related tasks relative to spatial visualizers. It is still unclear, in which stage the advantage appears. In this study, a behavioral experiment revealed that spatial visualizers' performance decreased evidently from short delay to long delay in a high-load(More)
Anemone flaccida Fr. Schmidt is used in the clinical compound prescription for the treatment of rheumatoid arthritis (RA) in China and has the traditional use of draining dampness, diminishing swelling, and relieving pain. Total saponins (TS) are the characteristic components and also the main active ingredients of A. flaccida. Previous reports indicated(More)
Osteoclasts, bone-specialized multinucleated cells, are responsible for bone destructive diseases such as rheumatoid arthritis and osteoporosis. Natural plant-derived products have received substantial attention given their potential therapeutic and preventive activities against bone destructive diseases. In the present study, we investigated the effects of(More)