Shivashankar Ravishankar

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INTRODUCTION Spinocerebellar ataxias (SCA) are a group of autosomal dominant ataxias with varied clinical phenotypes. However there are no unique distinguishing features on routine neuroimaging among the various genetically defined SCAs. Voxel-based morphometry (VBM) provides an automated unbiased analysis of structural MRI scans and gives a comprehensive(More)
INTRODUCTION Hippocampal complex and neocortex play distinct, complementary roles in processing of memory, which is impaired in patients with mesial temporal sclerosis (MTS). METHOD Ten right-sided MTS patients and 10 controls were prospectively assessed by functional Magnetic Resonance Imaging (fMRI) using encoding and retrieval of visual memory tasks.(More)
An 11-year-old girl manifested with photophobia, ptosis, external ophthalmoplegia, hypotonia, weakness of proximal limb muscles, hyporeflexia, and generalized seizures (six months). Her elder sister had had uncontrolled seizures and photophobia and died at seven years of age. In the patient, serum lactate was high (55 mg/dl). Muscle biopsy revealed(More)
BACKGROUND AND PURPOSE Reports of central pontine myelinolysis (CPM)-like changes in Wilson's disease (WD) and its sequential changes are exceptional. The aim was to study the MRI characteristics of CPM-like changes in WD and the serial changes. METHODS Among the 121 patients of WD, twenty (M:F:9:11, age at onset: 14.2 +/- 4.6 years) had features similar(More)
The frontal pole (FP), which largely overlaps with Brodmann's area (BA) 10, is the rostral-most part of the hominid cerebral cortex, and plays a critical role in complex aspects of human cognition. The existing conventions suggested for MRI-based parcellation of this important frontal subdivision have limited cytoarchitectonic meaning with regard to the(More)
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