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- Publications
- Influence
RP-LC Resolution of (R,S)-Atenolol via Diastereomerization with Marfey’s Reagent and Its Structural Variants Under Conventional and Microwave Heating
- R. Bhushan, Shivani Tanwar
- Chemistry
- 7 August 2008
Abstract(R,S)-Atenolol was derivatized with Marfey’s reagent, (MR; 1-fluoro-2,4-dinitrophenyl-5-l-alanine amide or FDNP-l-Ala-NH2) and its four structural variants (FDNP-l-Phe-NH2, FDNP-l-Val-NH2,… Expand
Synthesis of succinimidyl-(S)-naproxen ester and its application for indirect enantioresolution of penicillamine by reversed-phase high-performance liquid chromatography.
- R. Bhushan, Shivani Tanwar
- Chemistry, Medicine
- Journal of chromatography. A
- 31 October 2008
Synthesis of N-succinimidyl-(S)-2-(6-methoxynaphth-2-yl) propionate was carried out by the reaction of (S)-naproxen with N-hydroxysuccinimide in the presence of dicyclohexyl carbodiimide. It was… Expand
Innovative sampling and extraction methods for the determination of nonsteroidal anti-inflammatory drugs in water.
- Shivani Tanwar, M. Di Carro, E. Magi
- Chemistry, Medicine
- Journal of pharmaceutical and biomedical analysis
- 15 March 2015
Two different innovative approaches were used for the determination of nonsteroidal anti-inflammatory drugs (NSAIDs) in water: stir bar sorptive extraction (SBSE) and passive sampling, followed by… Expand
Reversed-phase liquid chromatographic determination of enantiomers of atenolol in rat plasma using derivatization with Marfey's reagent.
- R. Bhushan, Shivani Tanwar
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1 July 2009
An HPLC method was established for enantioseparation of (R,S)-atenolol (ATE) and determination of enantiomers in rat plasma. Marfey's reagent (1-fluoro-2,4-dinitrophenyl-5-L-alanine amide,… Expand
Study of Convolvulus pluricaulis for antioxidant and anticonvulsant activity.
- Sristi Verma, R. Sinha, Puspendra Kumar, Faizal Amin, J. Jain, Shivani Tanwar
- Chemistry, Medicine
- Central nervous system agents in medicinal…
- 29 February 2012
Convolvulus pluricaulis Choisy is a perennial wild herb commonly found on sandy & rocky areas under xerophytic conditions in northern India. It is a reputed drug of ayurveda and reported to posses… Expand
Reversed-phase high-performance liquid chromatographic enantioresolution of six beta-blockers using dinitrophenyl-L-Pro-N-hydroxysuccinimide ester, N-succinimidyl-(S)-2-(6-methoxynaphth-2-yl)…
- R. Bhushan, Shivani Tanwar
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1 December 2009
Twelve chiral derivatizing reagents (CDRs) were synthesized by substituting one of the fluorine atoms in 1,5-difluoro-2,4-dinitrobenzene (DFDNB) with three optically pure amines… Expand
Synthesis of dinitrophenyl-L-Pro-N-hydroxysuccinimide ester and four new variants of Sanger's reagent having chiral amines and their application for enantioresolution of mexiletine using…
- R. Bhushan, Shivani Tanwar
- Chemistry, Medicine
- Journal of chromatography. A
- 24 July 2009
Four chiral derivatizing reagents (CDRs) having enantiomerically pure amines and two CDRs namely, [N-succinimidyl-(S)-2-(6-methoxynaphth-2-yl)propionate], and… Expand
Different approaches of impregnation for resolution of enantiomers of atenolol, propranolol and salbutamol using Cu(II)-L-amino acid complexes for ligand exchange on commercial thin layer…
- R. Bhushan, Shivani Tanwar
- Chemistry, Medicine
- Journal of chromatography. A
- 19 February 2010
Atenolol and propranolol (the beta-blocking agents) and salbutamol (broncho- and vasodilator) were resolved into their enantiomers by adopting different modes of loading/impregnating the Cu(II)… Expand
Chromatographic separation of enantiomers of non-protein α-amino acids after derivatization with Marfey’s reagent and its four variants
- R. Bhushan, V. Kumar, Shivani Tanwar
- Chemistry, Medicine
- Amino Acids
- 1 March 2009
Some non-protein α-amino acids were derivatized with 1-fluoro-2,4-dinitrophenyl-5-l-alaninamide (Marfey’s reagent, MR, FDNP-l-Ala-NH2,) and four of its structural variants FDNP-l-Phe-NH2,… Expand
Enantioresolution of Amino Acids: A Decade’s Perspective, Prospects and Challenges
- Shivani Tanwar, R. Bhushan
- Chemistry
- Chromatographia
- 10 July 2015
Both from academic and industrial points of view enantioseparation of dl-amino acids continues to be a subject of immense importance and enjoys a great analytical significance in various fields, such… Expand