Shiu-Ching Chen

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At any time, over 1.4 million people worldwide are suffering from infections acquired in hospital. Approximate 380,000 to 450,000 preventable Adverse drug events (ADEs) occurring annually in the United States. Therefore, patient safety has become a serious global public health issue. The purpose of this paper attempts to improve medication safety and reduce(More)
The syndrome of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episode (MELAS) is typically associated with a single point mutation in the mitochondrial genome (mtDNA). Because mtDNA is known to have a higher mutation rate than nuclear DNA, we speculate that some patients with MELAS syndrome may harbor more than one mutation in mtDNA. For(More)
Organized glomerular electron-dense deposits with a fingerprint pattern are well known in some patients of lupus nephritis or cryoglobulinemia. In general, these two diseases are always discussed separately as the causes of such deposits. However, 3 of our 5 lupus patients with glomerular fingerprint deposits also had cryoglobulinemia. One of the remaining(More)
We report a 65-year-old woman with a sporadic form of progressive oculopharyngeal somatic myopathy due to a novel large-scale 3,399 base pair (bp) deletion of the mitochondrial DNA (mtDNA) and co-occurrence of a homoplasmic T5814C transition. The onset of myopathy began from chronic progressive external ophthalmoplegia (CPEO) at age of 20 years. Bulbar(More)
In developed countries as many as one in ten patients is harmed while receiving hospital care, estimates 1.4 million people worldwide suffer from infections acquired in hospitals, and approximate 380,000 to 450,000 preventable Adverse drug events (ADEs) occurring annually in the United States. Medical errors and ADEs could be prevented by building a safer(More)
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