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We consider the problem of common due window location scheduling on a single machine, where the processing times of jobs depend both on their starting times and positions in a sequence. The problem is to determine the optimal earliest due date, the due window size, and the job schedule simultaneously to minimize costs for earliness, tardiness, earliest due(More)
Rpb9, a nonessential subunit of RNA polymerase II (Pol II), has multiple transcription-related functions in Saccharomyces cerevisiae, including transcription elongation and transcription-coupled repair (TCR). Here we show that, in response to UV radiation, Rpb9 also functions in promoting ubiquitylation and degradation of Rpb1, the largest subunit of Pol(More)
In the papers by Kellerer et al. (1995) and Zhang (1997) the authors investigate a semi on-line version of a classical parallel machine scheduling problem. In the semi on-line version, there is a buffer of length k which is available to maintain k jobs. The jobs arrive one by one and can be temporarily assigned to the buffer if the buffer is not full. The(More)
Rad26, a DNA dependent ATPase that is homologous to human CSB, has been well known to play an important role in transcription coupled DNA repair (TCR) in the yeast Saccharomyces cerevisiae Sen1, a DNA/RNA helicase that is essential for yeast cell viability and homologous to human senataxin, has been known to be required for transcriptional termination of(More)
Covalent modifications of proteins by ubiquitin and the Small Ubiquitin-like MOdifier (SUMO) have been revealed to be involved in a plethora of cellular processes, including transcription, DNA repair and DNA damage responses. It has been well known that in response to DNA damage that blocks transcription elongation, Rpb1, the largest subunit of RNA(More)