Shiran Wijeratne

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Recent evidence suggests that cell-free plasma DNA has potential use as a prognostic marker in many clinical settings. The aim of the present study was to evaluate the prognostic role of cell-free plasma DNA in the prediction of clinical outcome in intensive treatment unit (ITU) patients. Cell-free plasma DNA was measured by real-time polymerase chain(More)
BACKGROUND Biological variation of an analyte is an important determinant of its usefulness. Intraindividual variation in serum thyroid hormones, parathyroid hormone (PTH) and insulin-like growth factor-1 (IGF-1) in healthy subjects was determined in this study. METHODS Blood samples were taken at weekly intervals for six weeks from 10 healthy subjects(More)
Verrucous carcinoma is a rare, well-differentiated variant of squamous cell carcinoma with a minimal incidence of metastasis. Conservative treatment and local excision have been utilized although with high recurrence rates. We present a unique case of a 44-year-old male with bilateral foot involvement with recurrences after local excision, leading to(More)
OBJECTIVE There is paucity of research documenting the management of splenic injury in rural Australia. No data exists for Rural, Remote and Metropolitan Area 4 locations. DESIGN A retrospective review of prospectively collected data. Records were additionally sought from transfer hospitals. A qualitative assessment of splenic trauma management in the(More)
Severe hypertriglyceridaemia is a rare presentation usually associated with acute pancreatitis. We present two case reports of severe hypertriglyceridaemia occurring in patients with previous autoimmune disease and haematological and solid malignancies but no evidence of prior or concurrent pancreatitis or hyperlipidaemia. These case reports illustrate that(More)
INTRODUCTION Little published data exists documenting the reasons for and outcomes of colectomies in rural Australia. It remains unclear whether patient characteristics, diagnoses, complications and outcomes differ to metropolitan locations. METHODS A retrospective review of prospectively collected data for patients coded with International Classification(More)
OBJECTIVE To determine the effect of the existing management protocol of patients presenting with acute urinary retention due to benign prostatic enlargement on clinical efficacy and surgical practice. DESIGN Prospective study. SETTING The Urology Unit at the Teaching Hospital, Karapitiya, Galle. PATIENTS 100 consecutive patients with a first episode(More)
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