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The Long Non-Coding RNA RHPN1-AS1 Promotes Uveal Melanoma Progression
- Linna Lu, Xiaoyu Yu, +10 authors X. Fan
- Biology, Medicine
- International journal of molecular sciences
- 1 January 2017
Increasing evidence suggests that aberrant long non-coding RNAs (lncRNAs) are significantly correlated with the pathogenesis, development and metastasis of cancers. RHPN1 antisense RNA 1 (RHPN1-AS1)… Expand
Prognostic factors for local recurrence, metastasis and survival for sebaceous carcinoma of the eyelid: observations in 100 patients
Background/aims To validate the predictive value of the American Joint Committee on Cancer (AJCC) 8th-edition classification for local recurrence, metastasis and survival in patients with eyelid… Expand
Pingyangmycin as first-line treatment for low-flow orbital or periorbital venous malformations: evaluation of 33 consecutive patients.
IMPORTANCE Low-flow orbital or periorbital venous malformation (OVM) is the most common periorbital vascular lesion that may produce an appearance defect, visual dysfunction, internal hemorrhage, and… Expand
Assessment of Choroidal Microstructure and Subfoveal Thickness Change in Eyes With Different Stages of Age-Related Macular Degeneration
AbstractAge-related macular degeneration (AMD) is a major cause of irreversible blindness. Choroidal structural changes seem to be inevitable in AMD pathogenesis. Our study revealed associated… Expand
ANRIL lncRNA triggers efficient therapeutic efficacy by reprogramming the aberrant INK4-hub in melanoma.
Melanoma is an extremely aggressive disease with rapid progression, high metastatic potential and recurrence. Simultaneous correction of multiple tumor-specific gene abnormalities has become an… Expand
BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells.
- H. Pan, Renbing Jia, +7 authors X. Fan
- Medicine, Biology
- The international journal of biochemistry & cell…
- 1 March 2015
Uveal melanoma (UM) is the most common form of primary intraocular malignancy in adult and has the tendency to metastasize. BAP1 mutations are frequently found in UM and are associated with a poor… Expand
Greater Tumor Thickness, Ulceration, and Positive Sentinel Lymph Node Are Associated With Worse Prognosis in Patients With Conjunctival Melanoma
- B. Esmaeli, M. Rubin, +5 authors Michael T. Tetzlaff
- The American journal of surgical pathology
- 14 August 2019
Supplemental Digital Content is available in the text. Identifying tumor characteristics that correlate with metastasis and survival in patients with conjunctival melanoma can potentially lead to… Expand
Validation Study of the AJCC Cancer Staging Manual, Eighth Edition, Staging System for Eyelid and Periocular Squamous Cell Carcinoma
Importance To our knowledge, there are no validation studies to date of the prognostic value of the AJCC Cancer Staging Manual, eighth edition (AJCC 8), criteria for eyelid and periocular squamous… Expand
Programmed death receptor Ligand 1 expression in eyelid sebaceous carcinoma: a consecutive case series of 41 patients
A limited number of therapies are available for patients with metastatic eyelid sebaceous carcinoma (SC). Programmed death receptor Ligand 1 (PD‐L1) expression and its clinical significance in… Expand
Treatment of periorbital infantile haemangiomas: A systematic literature review on propranolol or steroids
- Shiqiong Xu, Renbing Jia, S. Ge, M. Lin, X. Fan
- Journal of paediatrics and child health
- 1 April 2014
The aim of this study was to compare the efficacy and safety of propranolol versus corticosteroids for the treatment of periorbital infantile haemangiomas (IHs).