Environmental exposure to lead during developmental stages has been established as a potential cause of intellectual deficits. The high susceptibility of rapidly developing fetal and infant brains to external factors suggests that impairment of later cognitive functions may arise from relatively minor prenatal exposure to environmental lead levels. In this… (More)
Prenatal aluminum exposure may affect the development of the embryo and alter the capacity for learning and memory in adults. The chick embryo is a good experimental model to study the effect of prenatal toxin exposure on cognitive defects in offspring, because it eliminates maternal confounding variables. In the present study, we applied a one-trial… (More)
Lithium is the first line of therapeutic drugs used to treat both mania and depression in bipolar disorder. Although a body of research suggests that lithium acts as a cognitive enhancer, other animal studies suggest that lithium induces cognitive deficits. Comparatively, the effects of lithium on cognitive behaviour in these studies are inconsistent and… (More)
The title steroid, C(29)H(44)O(7), is a new androgen derivative and a key inter-mediate for synthesizing novel anti-HIV steroid agents. There are four trans-fused rings in the structure. The three six-membered rings exhibit chair conformations, while the five-membered ring adopts an envelope conformation.
The title compound, C(24)H(41)NO, is a new derivative of the anti-HIV steroid 17β-(N-tert-butyl-amino-carbon-yl)androst-4-en-3-one. There are four rings in the structure and these are trans-fused. The three six-membered rings exhibit chair conformations, while the five-membered ring adopts an envelope conformation.