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Agriculture faces great challenges to ensure global food security by increasing yields while reducing environmental costs. Here we address this challenge by conducting a total of 153 site-year field experiments covering the main agro-ecological areas for rice, wheat and maize production in China. A set of integrated soil-crop system management practices(More)
A 2-year field microplot experiment was conducted to determine the effects of nitrogen (N) splits on grain yields and the fate of 15N-labelled fertilizer applied to plastic mulched maize (Zea mays L.). Three N split applications at the same rate of 225 kg N hm−2 were performed. The N was applied at the day before sowing, the eight-leaf stage (V8), and the(More)
Recent structural studies of epidermal growth factor receptor (EGFR) family extracellular regions have identified an unexpected mechanism for ligand-induced receptor dimerization that has important implications for activation and inhibition of these receptors. Here we describe the 2.8 angstroms resolution X-ray crystal structure of the antigen binding (Fab)(More)
PURPOSE To evaluate the effects of tetramethylpyrazine (TMP) on retinal neovascularization (NV) and neuroprotection in an oxygen-induced retinopathy (OIR) model. METHODS Neonatal C57BL/6J mice were subjected to 75% oxygen from postnatal day 7 (P7) to P12 and then returned to room air. TMP (200 mg/kg) or normal saline was given daily from P12 to P17.(More)
The Loess Plateau of China has the highest soil erosion rate in the world where billion tons of soil is annually washed into Yellow River. In recent decades this region has experienced significant climate change and policy-driven land conversion. However, it has not yet been well investigated how these changes in climate and land use have affected soil(More)
PURPOSE To assess the effects of retro-orbital (RO) injection of fluorescein isothiocyanate dextran (FITC-dextran) for observing mouse retinal vessels. METHODS Oxygen-induced retinopathy (OIR) was induced in 7-day postnatal (P7) C57BL/6J mice by exposing them to a 75% oxygen atmosphere for 5 days and then returning them to room air at P12. At P17, 45 P17(More)
PURPOSE The purpose of the current study was to investigate the effect of topical administration of KH906 on corneal neovascularization (NV). METHODS To induce corneal neovascularization, chemical cauterization of the corneas of the right eyes of forty-eight New Zealand white rabbits was performed by touching the central cornea with an 8-mm-diameter(More)
Plastic film (FM) and gravel mulching (GM) have been used extensively to increase dryland agricultural productivity. Understanding mulching effects on nitrogen (N) use efficiency (NUE) and soil nitrogen dynamics is important for optimizing N management strategies. A 3-year field experiment was performed on the Loess Plateau of China to investigate the GM(More)
Increasing evidence indicates that current dynamic global vegetation models (DGVMs) have suffered from insufficient realism and are difficult to improve, particularly because they are built on plant functional type (PFT) schemes. Therefore, new approaches, such as plant trait-based methods, are urgently needed to replace PFT schemes when predicting the(More)
Methane (CH4) uptake by dryland soils is an important part in the global CH4 budget and is sensitive to the management practice. This research measured the annual CH4 flux over 2 years at the rain-fed maize fields in semiarid northwestern China using the static chamber technique. Methane uptake was measured under three mulching practices with the same(More)