Shintaro Tachibana

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BACKGROUND Recent findings suggest that acoustic cavitation is responsible for acceleration of thrombolysis by ultrasound (US) energy. It is known that albumin microbubbles lower the threshold of acoustic cavitation production. METHODS AND RESULTS The present study was designed to determine whether the presence of albumin microbubbles used for(More)
Severity-correlated enlargement of the median nerve occurs in idiopathic carpal tunnel syndrome (CTS). We determined whether measurement of the nerve cross-sectional area was useful in making the diagnosis of CTS. In 414 wrists of 275 patients with clinically diagnosed idiopathic CTS and 408 wrists of 408 controls, we made ultrasonographic measurements of(More)
PURPOSE To compare the outcomes of percutaneous carpal tunnel release (PCTR) and mini-open carpal tunnel release (mini-OCTR) using ultrasonographic guidance for both techniques. METHODS We included 74 hands of 65 women with idiopathic carpal tunnel syndrome (age, 52-71 y; mean, 58 y). Thirty-five hands of 29 women had the PCTR (release with a device(More)
BACKGROUND Currently available local anesthetics, such as EMLA (eutectic mixture of local anesthetics), have poor skin penetration when administrated topically. As 60 min is needed for EMLA to be fully effective, attempts to accelerate transdermal delivery of a local anesthetic, such as lidocaine, by use of "electrical" and "physical" energy has previously(More)
Ultrasound has been in use for the last three decades as a modality for diagnostic imaging in medicine. Recent studies have shown that nonthermal ultrasound energy could be applied for targeting or controlling drug release. This new concept of therapeutic ultrasound combined with drugs has induced interest in various medical fields. Enhanced effects of(More)
In this study, we examined the relationship between the frontal midline (Fm) theta rhythm that appears when a healthy subject is engaged in mental tasks and the theta rhythm which appears in the frontal region of healthy subjects during light drowsiness. The samples for this study were obtained from 465 EEGs of healthy Japan Air Self Defense Force(More)
INTRODUCTION Edoxaban is an oral, direct, once-daily factor Xa inhibitor. This study evaluated the safety and efficacy of edoxaban compared to subcutaneous enoxaparin in Japanese patients undergoing hip fracture surgery. MATERIALS AND METHODS In this multicenter, randomized, open-label, active-comparator, phase 3 trial, 92 patients were randomized 2:1 to(More)
Three types of blink reflex were evoked by 1) supraorbital nerve stimulation, 2) light flash stimulation and 3) corneal touch. The blink reflex response was recorded simultaneously for both eyes by electromyography of the orbicularis oculi muscles of the lower eyelid. After supraorbital nerve stimulation, ipsilateral early response (R1) and bilateral late(More)
Ultrasound is frequently used in medicine for diagnostic purposes. Recently, there have been numerous reports on application of ultrasound energy for controlling drug release or targeting. This new concept of therapeutic ultrasound combined with drugs has induced excitement in various areas. Ultrasound energy can enhance effects of thrombolytic agents as(More)