Shintaro Kugimiya

Learn More
We report that long-chain poly-L-glutamine forms cation-selective channels when incorporated into artificial planar lipid bilayer membranes. The channel was permeable to alkali cations and H(+) ions and virtually impermeable to anions; the selectivity sequence based on the single-channel conductance was H(+) >> Cs(+) > K(+) > Na(+). The cation channel was(More)
The molting hormonal activity of methoxyfenozide (RH-2485), tebufenozide (RH-5992), five analogs with various alkyl groups, and 18 acyl analogs was measured by using cultured integument of rice stem borers, Chilo suppressalis Walker. The hormonal activity of methoxyfenozide was remarkably high (EC(50) = 1.1 x 10(-9) M), being equivalent to that of(More)
Ninety-six patients whose diagnosis was definitively confirmed as primary generalized epilepsy (PGE) were divided into two groups according to the duration of recurrent seizures--A group for less than 7 years and B group for more than 7 years. The patients of both groups were completely free of seizures for more than 3 years at the time of the survey. A(More)
  • 1