Shinro Takai

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Proximal tibiofibular synostosis without multiple hereditary exostosis is extremely rare and only 7 cases have been reported in the literature. All of the previously reported cases accompanied deformities such as distal positioning of the proximal tibiofibular joint, leg length discrepancy, bowing of the fibula, and valgus deformity of the knee. The present(More)
To elucidate the behavior of autologously transplanted mesenchymal cells in osteochondral defects, we followed transplanted cells using green fluorescent protein (GFP) transgenic rats, in which all cells express GFP signals in their cytoplasm and nuclei as transplantation donors. Bone marrow-derived mesenchymal cells, which contain mesenchymal stem cells(More)
Computed tomography (CT) has been used to assess the rotational alignment of the distal femur. The purpose of this study was to establish a simple radiographic technique to evaluate the posterior femoral condyles. For this study, 39 osteoarthritic knees and 19 normal knees were examined. The condylar twist angle and posterior condylar angle were measured(More)
Rotational alignement of the lower limbs in 43 patients with osteoarthritis of the knee was measured by computerized tomography. Eighty-four limbs were classified in three subsets, patellofemoral osteoarthritis (subset P), medial femorotibial osteoarthritis (subset M) and lateral femorotibial osteoarthritis (subset L). The femorotibial angle of subset M was(More)
The objective of this study was to review the use of intramedullary supracondylar (IMSC) nails for distal femoral fractures. We reviewed 24 fractures treated with second-generation IMSC nails. The fractures consisted of 18 type A1, one type A2, two type C1, one type C2, and two type C3 fractures. The relationships between clinical results and fracture type,(More)
Osteochondritis dissecans in two adults with a large osteochondral defect on the weight-bearing surface was treated by transplantation of an autogeneic osteochondral fragment. The graft was transplanted from the normal portion of the medial femoral condyle, which in extension was in contact with neither patella nor meniscus. The donor site was repaired with(More)
An original tensor system was developed to directly measure the load between femoral trial component and tibial cut surface in vivo in both patella everted and reset positions during total knee arthroplasty (TKA). We used this system during posterior-stabilized (PS) and cruciate-retaining (CR) TKA. In PS-TKA, there was no significant difference between the(More)
BACKGROUND Molecular hydrogen (H2) functions as an extensive protector against oxidative stress, inflammation and allergic reaction in various biological models and clinical tests; however, its essential mechanisms remain unknown. H2 directly reacts with the strong reactive nitrogen species peroxynitrite (ONOO-) as well as hydroxyl radicals (•OH), but not(More)
In peripheral nerve allografts, use of an immunosuppressive agent is one of the ways of reducing nerve rejection. FK506 is a newly discovered substance, extracted from Streptomyces tsukubaensis, and has strong immunosuppressive effects. In the present study, immunosuppressive effects of FK 506 were examined using allografts of rat sciatic nerves. Good nerve(More)
OBJECTIVE The fate of transplanted cells used in tissue engineering strategies should be followed. With this aim in view, the survival of transplanted bone-marrow-derived mesenchymal cells within osteochondral defects was determined using transgenic rats to simulate autologous transplantation. DESIGN An autologous transplantation model was simulated using(More)