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Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance.
- J. Togawa, H. Nagase, +7 authors H. Sekihara
- American journal of physiology. Gastrointestinal…
- 1 July 2002
Natural immunomodulator lactoferrin is known to exert an anti-inflammatory effect. However, there have been no studies that examine the mode of action of lactoferrin in reducing intestinal damage. We… Expand
Analysis of Th1 and Th2 cytokine production by peripheral blood mononuclear cells as a parameter of immunological dysfunction in advanced cancer patients
- S. Goto, M. Sato, R. Kaneko, Masayoshi Itoh, Shinobu Sato, S. Takeuchi
- Cancer Immunology, Immunotherapy
- 1 November 1999
Purpose: The presence of immunological dysfunction has not been well demonstrated in cancer patients. Recent studies have revealed that the immune response can be classified into types 1 and 2, and… Expand
Characterization of lymphangiogenesis in various stages of idiopathic diffuse alveolar damage.
In pulmonary fibrosis, an abnormal healing process, is believed to be involved in the damage to lung tissue. This process has not been correlated with lymphangiogenesis, which has garnered current… Expand
Fluorescence imaging of potassium ions in living cells using a fluorescent probe based on a thrombin binding aptamer-peptide conjugate.
- K. Ohtsuka, Shinobu Sato, +8 authors S. Takenaka
- Chemistry, Medicine
- Chemical communications
- 18 April 2012
When a biotinylated FRET probe based on a peptide-thrombin binding aptamer conjugate was introduced together with streptavidin and biotinylated nuclear export signal peptide into HeLa cells, the… Expand
Electrochemical telomerase assay with ferrocenylnaphthalene diimide as a tetraplex DNA-specific binder.
- Shinobu Sato, H. Kondo, T. Nojima, S. Takenaka
- Medicine, Chemistry
- Analytical chemistry
- 20 October 2005
Spectroscopic studies revealed that ferrocenylnaphthalene diimide (1) can bind to tetraplex DNA at high potassium ion concentration. The tetraplex DNA was stabilized by the binding of 1, and this… Expand
Diagnosis of Periodontal Disease from Saliva Samples Using Fourier Transform Infrared Microscopy Coupled with Partial Least Squares Discriminant Analysis.
- S. Fujii, Shinobu Sato, +6 authors S. Takenaka
- Chemistry, Medicine
- Analytical sciences : the international journal…
- 10 February 2016
Diagnosis of periodontal disease by Fourier transform infrared (FT-IR) microscopic technique was achieved for saliva samples. Twenty-two saliva samples, collected from 10 patients with periodontal… Expand
The definition of fibrogenic processes in fibroblastic foci of idiopathic pulmonary fibrosis based on morphometric quantification of extracellular matrices.
There is limited information regarding the process of tissue remodeling in fibroblastic foci associated with idiopathic pulmonary fibrosis. The aim of this study was to identify the different… Expand
Electrochemical detection of aberrant methylated gene using naphthalene diimide derivative carrying four ferrocene moieties
Naphthalene diimide derivative, F4ND, carrying four ferrocene moieties was synthesized as a new hybridization indicator for electrochemical gene detection using DNA probe-immobilized electrode. F4ND… Expand
Selective immobilization of double stranded DNA on a gold surface through threading intercalation of a naphthalene diimide having dithiolane moieties.
Newly synthesized naphthalene diimide 1 having two dithiolane moieties at its substituted termini bound to double stranded DNA by threading intercalation and the resulting complex was immobilized on… Expand
Pulmonary Arterial Aneurysm with CATCH 22 Syndrome
An adult case of CATCH 22 syndrome with a pulmonary arterial aneurysm is presented. The chest radiograph showed a large massive lesion, which should be differentiated from lung cancer, mediastinal… Expand