Shinobu Kumaoka

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In 1979, the protocol guidelines on clinical assessment of response to therapy in advanced breast cancer were proposed by the Chemotherapy Committee and the Endocrine Therapy Committee of the Japan Mammary Cancer Society, in accordance with guidelines presented by the UICC (1977) and by the Breast Cancer Task Force of the NCI (1978). After amending some(More)
To define the role of asymptomatic autoimmune thyroiditis in the cause of breast cancer, the presence of circulating thyroid autoantibodies was studied in two populations, one with a high risk of breast cancer (British women) and one with a low risk (Japanese women). Ostensibly healthy women and patients with breast cancer from both countries were studied.(More)
Histopathologic features of the primary tumor and axillary lymph nodes from 97 consecutive patients with breast cancer from Japan were compared with those from 164 patients from England. Between the two groups, there were statistically significant differences in the morphology of the primary tumors regarding nuclear grade and patterns of tumor infiltration.(More)
Research on Dietary Fibre Dr G. A. Spiller, Dr R. J. Amen Urinary Reflux and Chronic Pyelonephritis Dr E. J. Evans Computer-assisted Tomography of the Brain Dr A. S. Bligh and others Minocyc1ine: Possihle Vestibular Side-effects Dr C. S. Nicol, Dr J. D. Oriel Antigenicity of Monocomponent Insulins J. Schlichtkrull Private Beds Prof. David Kerr, F.R.C.P.; Mr(More)
SiR.-In 1977, a project of the programme on clinical oncology of the UICC published a system of guide-lines recommended for use in clinical trials designed to assess the objective response of locally advanced or metastatic mammary cancer to treatment (Hayward et al., 1977). Since then it has become apparent that the rules for defining duration of remission(More)
A prospective study has been carried out to compare the response rates to endocrine therapy of Japanese and British women with breast cancer. Premenopausal women were treated by ovarian ablation, patients who were up to five years postmenopausal were prescribed androgen therapy and patients who were more than five years postmenopausal were treated with(More)