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OBJECT The aims of this study were to clarify the histological and histochemical changes associated with cell death in the spinal cord after acute traumatic injury and to examine the role of excitatory amino acid release mediated by N-methyl-D-aspartate (NMDA) receptors. METHODS Following laminectomy, the spinal cord in 70 rats was injured at the T-9(More)
OBJECTIVES Afghan asylum seekers in Japan were increasingly subject to detention following the terrorist attack in New York in September 2001, yet little is reported about the net impact of the detention on their mental health. We examined this by comparing asylum seekers who had once been detained in post-migration and their non-detained counterparts. (More)
The aims of this study were to clarify the mechanism of cell death by apoptosis in the spinal cord after traumatic injury, and to examine the role of the mitogen-activated protein kinase (MAPK) pathways in the transmission of apoptosis signals. The rat spinal cord, experimentally injured by extradural static weight-compression, was studied by hematoxylin(More)
BACKGROUND The aim of this study was to evaluate the available resources for trauma care at health centers (HCs) and referral hospitals (RHs) in rural Cambodia and to examine whether the resources at HCs are allocated on the basis of actual need based on the referral distance and number of severely injured patients referred to RHs. METHODS We conducted a(More)
The risk of death of unbelted rear-seat occupants is obviously increased in car crashes. However, there is little epidemiological evidence that unbelted rear-seat occupants will also increase the risk of death of front-seat passengers. We compared risk of death and severe injury of front-seat occupants in car crashes with belted or unbelted rear-seat(More)
STUDY DESIGN A histologic and histochemical study was performed both in the autopsy of a human patient with cervical spinal cord compression caused by ossification of the posterior longitudinal ligament and in a tiptoe-walking Yoshimura mouse model of progressive cervical cord compression. OBJECTIVES To clarify the mechanism of destructive pathologic(More)
OBJECTIVES This study aimed to investigate whether early epinephrine administration in out-of-hospital cardiopulmonary arrest (OHCA) patients was associated with improved outcomes and to address the selection bias inherent in observational studies (more severe cases are more likely to receive epinephrine). METHODS This was a retrospective analysis of(More)
BACKGROUND Cross-cultural use of the cutoff points determined in Indo-Chinese refugees of the Hopkins Symptom Checklist-25 (HSCL-25) and the Harvard Trauma Questionnaire (HTQ) is common in refugee mental health research but it might have caused misclassifications. METHODS We assessed the validity of the predetermined cutoff points in identifying(More)
Stigmatization by the general population and their negative attitudes towards leprosy negatively impacts on patients' mental health, and so too does patients' perception of that stigma. The objective of this present study is to assess the depressive status of leprosy patients, the patient perception of that stigma, and its association with their depressive(More)