Learn More
The aims of this study were to clarify the mechanism of cell death by apoptosis in the spinal cord after traumatic injury, and to examine the role of the mitogen-activated protein kinase (MAPK) pathways in the transmission of apoptosis signals. The rat spinal cord, experimentally injured by extradural static weight-compression, was studied by hematoxylin(More)
BACKGROUND The aim of this study was to evaluate the available resources for trauma care at health centers (HCs) and referral hospitals (RHs) in rural Cambodia and to examine whether the resources at HCs are allocated on the basis of actual need based on the referral distance and number of severely injured patients referred to RHs. METHODS We conducted a(More)
The risk of death of unbelted rear-seat occupants is obviously increased in car crashes. However, there is little epidemiological evidence that unbelted rear-seat occupants will also increase the risk of death of front-seat passengers. We compared risk of death and severe injury of front-seat occupants in car crashes with belted or unbelted rear-seat(More)
STUDY DESIGN A histologic and histochemical study was performed both in the autopsy of a human patient with cervical spinal cord compression caused by ossification of the posterior longitudinal ligament and in a tiptoe-walking Yoshimura mouse model of progressive cervical cord compression. OBJECTIVES To clarify the mechanism of destructive pathologic(More)
OBJECT The aims of this study were to clarify the histological and histochemical changes associated with cell death in the spinal cord after acute traumatic injury and to examine the role of excitatory amino acid release mediated by N-methyl-D-aspartate (NMDA) receptors. METHODS Following laminectomy, the spinal cord in 70 rats was injured at the T-9(More)
OBJECTIVES This study aimed to investigate whether early epinephrine administration in out-of-hospital cardiopulmonary arrest (OHCA) patients was associated with improved outcomes and to address the selection bias inherent in observational studies (more severe cases are more likely to receive epinephrine). METHODS This was a retrospective analysis of(More)
We assessed unsafe sexual behaviors of the Nepalese HIV-positive men and their knowledge about the consequences of unsafe sex. We interviewed 167 participants recruited conveniently in the Kathmandu Valley, Nepal. Of total, 125 participants (75%) had sex in the past 6 months, 47% of whom with multiple partners. Fifty-seven (46%) of 123 participants who had(More)
Unprotected sexual intercourse among HIV-positive people can adversely affect their own health by increasing their exposure to multiple strains of HIV-1 or other sexually transmitted infections (STIs). The study explored the relationship between knowledge of Nepalese HIV-positive men about the consequences of having unprotected sex with seroconcordant(More)
In an attempt to address rapidly increasing injuries in low-income and middle-income countries (LMICs), the Essential Trauma Care Project was started with the goal of standardizing trauma care systems. This project, although part of "vertical" essential health services, has the potential to strengthen the health care system as a whole and to empower(More)
OBJECTIVES To evaluate the effectiveness of pre-hospital adrenaline (epinephrine) administered by emergency medical services to patients with out of hospital cardiac arrest. DESIGN Controlled propensity matched retrospective cohort study, in which pairs of patients with or without (control) adrenaline were created with a sequential risk set matching based(More)