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We propose a real-time gaze estimation method based on facial-feature tracking using a single video camera that does not require any special user action for calibration. Many gaze estimation methods have been already proposed; however, most conventional gaze tracking algorithms can only be applied to experimental environments due to their complex(More)
Bone marrow (stem/progenitor) cells have been shown to "differentiate" into cells in multiple tissues, including lung. A low number of hematopoietic stem/progenitor cells also circulate in peripheral blood. The physiologic roles of these cells are still uncertain. This study was designed to test, using parabiotic mice that were joined surgically, whether(More)
Reminiscence therapy, which is effective for increasing the selfesteem of and for reducing behavioral disturbances in individuals with dementia, is usually conducted in a group led by experienced staff. However, due to the shortage of care attendants, only a limited number of patients at home can receive the benefits of this therapy. To provide this therapy(More)
Matrix metalloproteinase-9 (MMP-9) is a matrix-degrading enzyme implicated in many biological processes, including inflammation. It is produced by many cells, including fibroblasts. When cultured in three-dimensional (3D) collagen gels, fibroblasts contract the surrounding matrix, a function that is thought to model the contraction that characterizes both(More)
This paper proposes a gaze-communicative stuffed-toy robot system with joint attention and eye-contact reactions based on ambient gaze-tracking. For free and natural interaction, we adopted our remote gaze-tracking method. Corresponding to the user's gaze, the gaze-reactive stuffed-toy robot is designed to gradually establish 1) joint attention using the(More)
In this paper, we present preliminary work we have done o n designing the TactaPack, a wearable sensor/actuator device that uses a Bluetooth wireless connection to return sensor data to a host, and to receive commands to initiate expressive vibrotactile stimuli. We present our work in the context of a physical therapy application designed to provide more(More)
Podoplanin (Aggrus), which is a type I transmembrane sialomucin-like glycoprotein, is highly expressed in malignant pleural mesothelioma (MPM). We previously reported the generation of a rat anti-human podoplanin Ab, NZ-1, which inhibited podoplanin-induced platelet aggregation and hematogenous metastasis. In this study, we examined the antitumor effector(More)
Since their advent, interaction with computers has been a very fascinating field of research. Though, we have come a long way from turning knobs and punching cards to using keyboards and pointing devices, natural language interaction has not seen widespread use as a general means of interaction. The thesis of this paper is that some application fields,(More)
Cytokines derived from lymphocytes are believed to play key roles in a variety of diseases, including airway diseases such as asthma. The current study was designed to evaluate the hypothesis that cytokines derived from Th2 cells, interleukin (IL)-4 and IL-13, might contribute to tissue remodeling by modulating the production of transforming growth factor(More)