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Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.
- Y. Kondo, T. Sasaki, +11 authors A. Ishigami
- Chemistry, Medicine
- Biochemical and biophysical research…
- 5 December 2008
Vitamin C (VC) has a strong antioxidant function evident as its ability to scavenge superoxide radicals in vitro. We verified that this property actually exists in vivo by using a real-time imaging… Expand
Ascorbic acid deficiency leads to epidermal atrophy and UVB-induced skin pigmentation in SMP30/GNL knockout hairless mice.
Structural Basis of the γ-Lactone-Ring Formation in Ascorbic Acid Biosynthesis by the Senescence Marker Protein-30/Gluconolactonase
The senescence marker protein-30 (SMP30), which is also called regucalcin, exhibits gluconolactonase (GNL) activity. Biochemical and biological analyses revealed that SMP30/GNL catalyzes formation of… Expand
Absorption and excretion of ascorbic acid alone and in acerola (Malpighia emarginata) juice: comparison in healthy Japanese subjects.
- Eriko Uchida, Y. Kondo, +7 authors A. Ishigami
- Medicine, Chemistry
- Biological & pharmaceutical bulletin
- 1 November 2011
It has been suggested that some food components, such as bioflavonoids, affect the bioavailability of ascorbic acid in humans. Since little is known in Japan about the effective intake of this… Expand