Shin-ichiro Umemura

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In this study, we investigated the induction of apoptosis by ultrasound in the presence of the novel porphyrin derivative DCPH-P-Na(I). HL-60 cells were exposed to ultrasound for up to 3 min in the presence and absence of DCPH-P-Na(I), and the induction of apoptosis was examined by analyzing cell morphology, DNA fragmentation, and caspase-3 activity.(More)
BACKGROUND A noninvasive technique to monitor thermal lesion formation is necessary to ensure the accuracy and safety of high-intensity focused ultrasound (HIFU) treatment. The purpose of this study is to ultrasonically detect the tissue change due to thermal coagulation in the HIFU treatment enhanced by cavitation microbubbles. METHODS An ultrasound(More)
Motion-Compensated Time-Averaged Imaging (MTI), a method of accumulating frames with a motion compensation technique using small subregions was conducted to improve Power Doppler and B-mode imaging. In our previous study, MTI was shown to be able to clearly image vasculature with contrast agents without image blurring even if the target tissue was moving(More)
A target tissue can be thermally coagulated in high-intensity focused ultrasound (HIFU) treatment noninvasively. HIFU thermal treatments have been clinically applied to various solid tumors. One of the problems in HIFU treatments is a long treatment time. Acoustically driven microbubbles can accelerate the ultrasonic heating, resulting in the significant(More)
We propose a new estimation method of tissues stiffness from deformation induced by arterial pulsation. The new method was named Intrinsic Elastography (IE). Under two assumptions that the deformation induced by pulsation propagates throughout the body, and the propagation velocity (PV) is closely related to the mechanical properties of tissues, the IE can(More)
OBJECTIVE To examine how connective tissue diseases affect finger-vein pattern authentication. METHODS The finger-vein patterns of 68 patients with connective tissue diseases and 24 healthy volunteers were acquired. Captured as CCD (charge-coupled device) images by transmitting near-infrared light through fingers, they were followed up in once in each(More)
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