Shin Yan Man

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BACKGROUND Community-acquired pneumonia (CAP) is a leading infectious cause of death throughout the world, including Hong Kong. AIM To compare the ability of three validated prediction rules for CAP to predict mortality in Hong Kong: the 20 variable Pneumonia Severity Index (PSI), the 6-point CURB65 scale adopted by the British Thoracic Society and the(More)
BACKGROUND Keratitis-ichthyosis-deafness (KID) syndrome is a rare congenital disorder characterized by the association of skin lesions, hearing loss and vascularizing keratitis. KID syndrome is caused by autosomal dominant mutations in the connexin 26 gene (GJB2). OBJECTIVES To establish whether there is a correlation between genotype and phenotype in KID(More)
BACKGROUND AND OBJECTIVE Agents such as Mycoplasma pneumoniae, Chlamydophila pneumoniae and Legionella pneumophila are recognized as important causes of community-acquired pneumonia (CAP) worldwide. This study examined the role of these 'atypical pathogens' (AP) among adult hospitalized patients with CAP. METHODS A prospective, observational study of(More)
OBJECTIVE To improve the understanding of the determinants of prognosis and accurate risk stratification in community-acquired pneumonia (CAP). DESIGN Multicentre collaboration of prospective cohorts. SETTING 6 cohorts from the USA, Canada, Hong Kong and Spain. PARTICIPANTS From a published meta-analysis of risk stratification studies in CAP, the(More)
INTRODUCTION Numerous prognostic predictive models have been developed for critically ill patients, many of which are primarily designed for use in intensive care units. The objective of this study was to evaluate the accuracy of a modified Acute Physiology and Chronic Health Evaluation (APACHE II) scoring system in predicting the mortality for critically(More)
Background: Community-acquired pneumonia (CAP) is a leading infectious cause of death throughout the world, including Hong Kong. Aim: To compare the ability of three validated prediction rules for CAP to predict mortality in Hong Kong: the 20 variable Pneumonia Severity Index (PSI), the 6-point CURB65 scale adopted by the British Thoracic Society and the(More)
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