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(1) To compare the serum levels of Dickkopf-1 (DKK-1) and bone biomarkers in patients with ankylosing spondylitis (AS) and healthy controls. (2) To examine the effects of anti-tumor necrosis factor-α (TNF-α) therapy for 3 months on bone biomarkers in patients with AS. We measured the levels of DKK-1, osteocalcin, osteoprotegerin, and C-terminal telopeptide(More)
OBJECTIVE We investigated the association between job stress and insomnia in a large nationwide samples of Korean workers. METHODS In this cross-sectional study, a total of 8,155 workers from a nationwide sample were recruited. We surveyed the subjects' socio-demographic and work-related characteristics and seven subscales of occupational stress using the(More)
OBJECTIVES The purpose of this study was to investigate the association between organochlorine (OC) pesticides and the prevalence of peripheral arterial disease (PAD). METHODS AND RESULTS This study included 2032 participants from the National Health and Nutrition Examination Survey (1999-2004), in which the ankle brachial index (ABI) and serum levels of(More)
OBJECTIVE This study was conducted to investigate the association between depressive symptoms and job stress, as measured by the KOSS, among Korean employees in small- and medium-sized enterprises, and examined which components of stress are involved in the risk for depression among males and females. METHODS Data were collected from a work-stress survey(More)
BACKGROUND/AIMS Our aim was to assess whether short-term treatment with soluble tumor necrosis factor (TNF) receptor affects circulating markers of bone metabolism in rheumatoid arthritis (RA) patients. METHODS Thirty-three active RA patients, treated with oral disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids for > 6 months, were(More)
OBJECTIVE We introduce the use of (99m)Tc-hydroxymethylene diphosphonate (HDP) digital blood flow scintigraphy to diagnose Raynaud's phenomenon (RP). METHODS Fifty-seven patients with RP and 60 healthy controls were recruited. One hand was chilled by immersion into water at 4 degrees C, and then an intravenous bolus of 740 MBq of (99m)Tc-HDP was injected.(More)
OBJECTIVES This survey was designed to determine whether depressive symptoms had an effect on the risk of self-reported occupational injury in South Korea. METHODS We conducted a prospective follow-up survey of workers at 44 small- to medium-sized companies classified into manufacturing or service businesses; 1,350 questionnaires were used in the final(More)
Inflammation has been known to be an important underlying condition for development of various diseases including cancer. The aims of this study were to investigate whether tobacco smoke exposure increases the level of inflammation biomarkers and the GSTM1 and GSTP1 gene polymorphisms are associated with inflammatory response due to tobacco smoke exposure.(More)
OBJECTIVE Although the effect of occupation or employment status on suicide risk is notable, there are few studies on the effect of precarious employment on suicide. We compared suicidal ideation and suicide attempts in precarious workers and their non-precarious counterparts using a representative sample from South Korea. METHOD The 2008 Korean Community(More)
OBJECTIVE The purpose of this study was to investigate the correlation between symptoms of depression in workers and the common cold. METHODS A follow-up survey of workers at 44 small- to medium-sized companies was conducted; 1350 questionnaires were used in the final analysis. The first survey requested information regarding personal information, work(More)