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OBJECTIVE It remains largely unknown whether tumor-associated macrophages (TAMs) are involved in invasion and metastasis of human lung cancer. The aim of our study was to obtain an accurate overview of the broad range of changes occurring in monocytes that develop into TAMs, and the roles of TAMs during the progression of non-small cell lung cancer. (More)
In this thesis, we develop tools and methods to assist in veri cation of large software systems. In particular, we will apply the complete coverage principle to generate test cases automatically from tabular expressions used in software documentation. Multi-dimensional expressions called tables are used in software documentation so that formal documentation(More)
Clusterin is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution. It plays important roles in various pathophysiological processes, including tissue remodeling, reproduction, lipid transport, complement regulation, and apoptosis. Clusterin appears to have two main isoforms that result from alternative splicing. The secreted and nuclear(More)
PURPOSE This study investigated the accuracy of intraoperative frozen section (FS) diagnosis for predicting the final pathology (FP) of peripheral small-sized lung adenocarcinoma and evaluated its usefulness in sublobar resection. PATIENTS AND METHODS The records of 803 patients with clinical stage I peripheral lung adenocarcinoma who underwent sublobar(More)
In an effort to reduce the morbidity and mortality associated with open esophagectomy, a minimally invasive approach to esophagectomy was introduced at the University of Pittsburgh Medical Center (UPMC) in 1996. The objective of this article is to discuss the optimization and refinement of minimally invasive esophagectomy (MIE) techniques over the 15-year(More)
Double-lumen endotracheal tube (DLET) anaesthesia is the commonly used method in minimally invasive oesophagectomy (MIE). However, DLET intubation does have its disadvantages. Firstly, the placement of the DLET needs a skilled anaesthetist with familiarity of the technique and subsequent ability to perform a fibre-optic bronchoscopy for confirmation.(More)
Finger-vein recognition as a non-contact biometric technique has its inherent superiority on accuracy, speed, sanitation, maintenance and security. However, we found that due to posture changes when acquiring finger images, the discrepancy between different images from the same finger greatly lowers the performance of the entire system. In this paper, we(More)
Sulfur mustard (HD) adduct to human serum albumin (ALB) at Cys-34 residue has become an important and long-term retrospective biomarker of HD exposure. Here, a novel, sensitive, and convenient approach for retrospective quantification of HD concentration exposed to plasma was established by detection of the HD-ALB adduct using ultra-high pressure liquid(More)
Finger vein recognition is a newly developed and promising biometrics technology. In current researches, finger vein recognition algorithms are mostly evaluated on data collected in laboratory environment. Along with its development, this technology gradually transforms from laboratory to actual use. Finger vein images captured in operational systems are(More)