Shikhar Kumar

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Effect of antidepressant drugs (amitriptyline, imipramine and fluoxetine) on cognitive functions, impaired by the muscarinic antagonist scopolamine were investigated in mice. The changes in learning and memory tasks were studied using transfer latency on elevated plus maze and employing number of descents in passive avoidance paradigms. Amitriptyline and(More)
  • Ratika Pradhan, Shikhar Kumar, Ruchika Agarwal, Mohan P Pradhan, M K Ghose, M K Ghose
  • 2010
Topographic maps contain information related to roads, contours, landmarks, land covers and rivers etc. For any Remote sensing and GIS based project, creating a database using digitization techniques is a tedious and time consuming process especially for contour tracing. Contour line is very important information that these maps provide. They are mainly(More)
BACKGROUND Clinico-epidemiological profile of the Human immunodeficiency virus (HIV) epidemic in India is varied and depends on multitude of factors including geographic location. We analyzed the characteristics of HIV-infected patients attending our Immunodeficiency Clinic to determine any changes in their profile over five years. SETTINGS AND DESIGN A(More)
BACKGROUND AND OBJECTIVE Acute exacerbation of chronic obstructive pulmonary disease (COPD) leads to increased morbidity, mortality and requirement of invasive mechanical ventilation (MV). The aim of this study was to identify predictors of need of MV in these patients. MATERIALS AND METHODS Clinical symptomatology, demographic profile, biochemical(More)
BACKGROUND The aim of this study is to identify the factors responsible for interruption of planned treatment in patients of carcinoma mid-thoracic esophagus and also discuss the strategies for improving treatment completion rates. MATERIALS AND METHODS Patients with nonmetastatic mid-thoracic esophageal cancer who received treatment by multimodality(More)
INTRODUCTION Sepsis is common presenting illness to the emergency services and one of the leading causes of hospital mortality. Researchers and clinicians have realized that the systemic inflammatory response syndrome concept for defining sepsis is less useful and lacks specificity. The predisposition, infection (or insult), response and organ dysfunction(More)
The goal of this paper is to study how people do relational reasoning, such as selecting the grade of all students in a class with GPA (Grade Point Average) greater than 3.5. Literature in the field of psychology of human reasoning offer little insight as to how people solve relational problems. We present two studies that look at human performance in(More)
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