Shikha Agarwal

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Explosive growth of data on the web demand techniques, which would enable the user to access desired information. In Information retrieval Document Classification is prerequisite. In practice many classification techniques were and are in use. Term Frequency-Inverse Document Frequency (TF-IDF) is an approach which represents documents based on the frequency(More)
In order to enhance the bioavailability of curcumin its conjugates with piperic acid and glycine were synthesized by esterifying the 4 and 4' phenolic hydroxyls, the sites of metabolic conjugation. Antiproliferative and apoptotic efficacy of synthesized conjugates was investigated in MCF-7 and MDA-MB-231 cell lines. IC50 values of di-O-glycinoyl (CDG) and(More)
Curcumin has been reported to be therapeutically active but has poor bioavailability, half life, and high rate of metabolic detoxifcation. Most of the hydrophobic and acidic drugs get transported through human serum albumin (HSA). Binding of drugs to serum protein increases their half-life. The present study is focused to analyze interaction of curcumin(More)
Online news reading is becoming an important part of the daily routine of online web users. The amount of information available online is increasing exponentially. Although this information is a valuable resource but lots of scattered, unstructured, irrelevant data is increasing on the web every moment which limits its value. Many research projects and(More)
To provide personalized services of digital product NEWS, complete understanding of user profile is very essential and crucial. It is observed that user interest in online news reading is very dynamic so we are making two profiles of each user: one for short term (dynamic) interests and one for long term (static) interests. We have designed an online news(More)
Curcumin is the yellow pigment of Curcuma longa that irreversibly inhibits the activity of thioredoxin reductase (TrxR) and forms adduct. TrxR, a homodimeric enzyme with E and F chains, is responsible for redox control of the cell and defense against oxidative stress. It is also well known that TrxR is over-expressed in tumor cells. Hence TrxR is a(More)
Isoproturon is the only herbicide that can control Phalaris minor, a competitive weed of wheat that developed resistance in 1992. Resistance against isoproturon was reported to be due to a mutation in the psbA gene that encodes the isoproturon-binding D1 protein. Previously in our laboratory, a triazole derivative of isoproturon (TDI) was synthesized and(More)
Aim of our research is to achieve user’s trust in our designed Semantic News Recommender System (SNRS). The work enriches the news items with automatic semantic annotations by adding additional layer in SNRS which will help in achieving user satisfaction by correctly inferring predictions of user interests in news domain. DBpedia has been used as an(More)
In today's online world users are suffering with the problem of information overload. To handle this problem, recommender systems assist users in giving required information by filtering out irrelevant information. So, most of the recommender systems mainly strive to achieve only accuracy in recommendations but this is not just what users want. Users(More)
Social Networks are imperative source of data analysis due to availability of data in high volume. Data available on these social networks have diverse features and utilities for different organizations. Marketing of brands on social networks is a vital step for business organizations these days. Customer brand perceptions and their purchasing decisions are(More)