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Precise glioma targeting of and penetration by aptamer and peptide dual-functioned nanoparticles.
The treatment of a brain glioma is still one of the most difficult challenges in oncology. To effectively treat brain glioma and reduce the side effects, drugs must be transported across the bloodExpand
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Angiopep-2 and activatable cell-penetrating peptide dual-functionalized nanoparticles for systemic glioma-targeting delivery.
Gliomas are hard to treat because of the two barriers involved: the blood-brain barrier and blood-tumor barrier. In this study, a dual-targeting ligand, angiopep-2, and an activatableExpand
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Efficient and Effective Sparse LSTM on FPGA with Bank-Balanced Sparsity
Neural networks based on Long Short-Term Memory (LSTM) are widely deployed in latency-sensitive language and speech applications. To speed up LSTM inference, previous research proposes weight pruningExpand
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Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization
Nanoparticles (NPs) were widely used in drugs/probes delivery for improved disease diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application of NPs. However,Expand
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Whole-cell SELEX aptamer-functionalised poly(ethyleneglycol)-poly(ε-caprolactone) nanoparticles for enhanced targeted glioblastoma therapy.
Though there has been substantial advancement in the knowledge about tumour development and treatment in the past 40 years, the prognosis of brain glioblastoma is still very grim due to theExpand
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Tumor cells and neovasculature dual targeting delivery for glioblastoma treatment.
Glioblastoma multiforme (GBM), one of the most common primary malignant brain tumors, was characterized by angiogenesis and tumor cells proliferation. Antiangiogenesis and antitumor combinationExpand
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Balanced Sparsity for Efficient DNN Inference on GPU
In trained deep neural networks, unstructured pruning can reduce redundant weights to lower storage cost. However, it requires the customization of hardwares to speed up practical inference. AnotherExpand
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Berberine metabolites could induce low density lipoprotein receptor up-regulation to exert lipid-lowering effects in human hepatoma cells.
Berberine (BBR) is an isoquinoline alkaloid isolated from several Chinese herbal medicines, such as Coptis chinensis, Berberis aristata, and Coptis japonica. It exhibits a lipid-lowering effect byExpand
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RGD and interleukin-13 peptide functionalized nanoparticles for enhanced glioblastoma cells and neovasculature dual targeting delivery and elevated tumor penetration.
As the most common malignant brain tumors, glioblastoma multiforme (GBM) was characterized by angiogenesis and tumor cells proliferation. Dual targeting to neovasculature and GBM cells could deliverExpand
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CORRIGENDUM: Ligand modified nanoparticles increases cell uptake, alters endocytosis and elevates glioma distribution and internalization
Nanoparticles (NPs) were widely used in drugs/probes delivery for improved disease diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application of NPs. However,Expand
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