Shihua Wen

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BACKGROUND The Problem formulation, Objectives, Alternatives, Consequences, Trade-offs, Uncertainties, Risk attitude, and Linked decisions (PrOACT-URL) framework and multiple criteria decision analysis (MCDA) have been recommended by the European Medicines Agency for structured benefit-risk assessment of medicinal products undergoing regulatory review. (More)
BACKGROUND A semiparametric density ratio method which borrows strength from two or more samples can be applied to moving window of variable size in cluster detection. The method requires neither the prior knowledge of the underlying distribution nor the number of cases before scanning. In this paper, the semiparametric cluster detection procedure is(More)
Title of dissertation: Semiparametric Cluster Detection Shihua Wen Doctor of Philosophy, 2007 Dissertation directed by: Professor Benjamin Kedem Mathematical Statistics Program Department of Mathematics In this dissertation, a Semiparametric density ratio testing method which borrows strength from two or more samples is applied to moving windows of variable(More)
An important goal of research on the cognitive neuroscience of decision-making is to produce a comprehensive model of behavior that flows from perception to action with all of the intermediate steps defined. To understand the mechanisms of perceptual decision-making for an auditory discrimination experiment, we connected a large-scale, neurobiologically(More)
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