Shih-Ying Huang

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PURPOSE Accurate anatomical characterization of the breast is useful in breast phantom development and computer modeling of breast imaging technologies. Capitalizing on the three-dimensional capabilities of dedicated breast CT (bCT), a number of parameters which describe breast shape and fibroglandular distribution are defined. METHODS Among 219 bCT data(More)
The purpose of this study was to examine the spatial resolution of a prototype pendant-geometry cone-beam breast computed tomography (CT) system. Modulation transfer functions (MTFs) of the reconstructed image in the coronal (x and y) plane were computed as a function of the cone angle, the radial distance from the axis of rotation, the size of the(More)
The noise power properties of a cone-beam computed tomography (CT) system dedicated for breast cancer detection were investigated. Uniform polyethylene cylinders of various diameters were scanned under different system acquisition conditions. Noise power spectra were calculated from difference data generated by subtraction between two identical scans.(More)
PURPOSE A simplified linear model approach was proposed to accurately model the response of a flat panel detector used for breast CT (bCT). METHODS Individual detector pixel mean and variance were measured from bCT projection images acquired both in air and with a polyethylene cylinder, with the detector operating in both fixed low gain and dynamic gain(More)
PURPOSE To quantify contrast material enhancement of breast lesions scanned with dedicated breast computed tomography (CT) and to compare their conspicuity with that at unenhanced breast CT and mammography. MATERIALS AND METHODS Approval of the institutional review board and the Radiation Use Committee and written informed consent were obtained for this(More)
Iodine-131-m-iodobenzylguanidine ([131I]mIBG)-targeted radionuclide therapy (TRT) is a standard treatment for recurrent or refractory neuroblastoma with response rates of 30–40 %. The aim of this study is to demonstrate patient-specific dosimetry using quantitative [124I]mIBG positron emission tomography/X-ray computed tomography (PET/CT) imaging with a(More)
The effect of breast skin thickness on dosimetry in mammography was investigated. Breast computed tomography (CT) acquisition techniques, combined with algorithms designed for determining specific breast metrics, were useful for estimating skin thickness. A radial-geometry edge detection scheme was implemented on coronal reconstructed breast CT (bCT) images(More)
PURPOSE The current study aimed to experimentally identify the optimal technique factors (x-ray tube potential and added filtration material/thickness) to maximize soft-tissue contrast, microcalcification contrast, and iodine contrast enhancement using cadaveric breast specimens imaged with dedicated breast computed tomography (bCT). Secondarily, the study(More)
Simultaneous imaging systems combining positron emission tomography (PET) and magnetic resonance imaging (MRI) have been actively investigated. A PET/MR imaging system (GE Healthcare) comprised of a time-of-flight (TOF) PET system utilizing silicon photomultipliers (SiPMs) and 3-tesla (3T) MRI was recently installed at our institution. The small-ring (60 cm(More)