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The tumor suppressor gene p53 has been implicated in the regulation of epithelial-mesenchymal transition (EMT) and tumor metastasis by regulating microRNA (miRNA) expression. Here, we report that mutant p53 exerts oncogenic functions and promotes EMT in endometrial cancer (EC) by directly binding to the promoter of miR-130b (a negative regulator of ZEB1)(More)
Agricultural soil is a major source of nitrous oxide (N2O), and the application of nitrogen and soil drainage are important factors affecting N2O emissions. This study tested the use of polymer-coated urea (PCU) and polymer-coated urea with the nitrification inhibitor dicyandiamide (PCUD) as potential mitigation options for N2O emissions in an imperfectly(More)
To understand which soil chemical properties are the best predictors of CH4 production in rice paddy soils, a model was developed with empirical data from nine types of rice soils collected around Japan and anaerobically incubated at 30 degrees C for 16 wk in laboratory conditions. After 1, 2, 4, 8, and 16 wk of incubation, CO2, CH4, and Fe(II) were(More)
Water management practices, such as midseason drainage (MD) and intermittent irrigation, are effective in reducing methane (CH4) emission from irrigated rice paddies. In a previous study in which two-year field experiments were conducted at nine sites across Japan, prolonged MD was found to reduce the seasonal total CH4 emission by 30.5 ± 6.7 % (mean ± 95 %(More)
The use of N fertilizers for agricultural production acts as a sources of atmospheric $$\hbox {N}_2\hbox {O}$$ N 2 O . Fertilizer induced $$\hbox {N}_2\hbox {O}$$ N 2 O emission considerably varies in accordance with environmental factors. We conducted a $$\hbox {N}_2\hbox {O}$$ N 2 O flux measurement campaign across 10 different experimental sites with(More)
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