Shigeru Matsumoto

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BACKGROUND Basic fibroblast growth factors (bFGFs) play a crucial role in wound healing by promoting fibroblast proliferation and neovascularization. However, drawback of bFGF is short half-life in free form. Gelatin has a capability of sustaining growth factors, which are gradually released while degradation. The purpose of this study is to see whether(More)
This study examined whether the specific inhibition of neutrophil elastase by sivelestat sodium hydrate (sivelestat) reduced deaths associated with severe acute lung injury after hydrochloric acid (HCl) aspiration in hamsters. Animals that received a single intratracheal instillation of HCl (0.2 N, 200 microL) time-dependently died by occlusion of their(More)
Many kinds of drug, such as anesthetics, muscle relaxants, blood products and others, are reported to be causes to anaphylaxis or anaphylactoid reaction during induction of anesthesia and operationl 5 . Incompatible transfusion obviously cause hemolytic adverse reaction, and in a patient with antiHLA antibody, transfusion of whole blood and packed cell(More)
In recent years, weaning from the cardiopulmonary bypass in open heart surgery has been made easy by the development of myocardial protection, and postoperative cardiac failure has decreased as well", However, weaning from the cardiopulmonary bypass has continued to be difficult in patients with decreased cardiac function or myocardial damage before(More)
Although most thymocytes express high levels of Fas antigen (CD95), the role of Fas in apoptosis signaling during thymocyte maturation has not been defined. Fas apoptosis occurs primarily in the CD4+CD8+ subpopulations of thymocytes. Fas expression and apoptosis function were investigated in the CD4−8−, CD4+8+, and CD4+ and CD8 single positive thymocyte(More)
This paper proposes a method that discovers trend rules from complex sequential data. The rules represent relationships among evaluation objects, keywords, and changes of numerical values related to the evaluation objects. The data is composed of numerical sequential data and text sequential data. The method extracts frequent patterns from transaction sets(More)
People use various information sources to resolve service quality uncertainty. This paper focuses on word-of-mouth communication among mothers. We conduct a survey of mothers with children in kindergarten to determine whether they use information from their friends on the choice of kindergartens and children’s clinics. We identify the factors that influence(More)