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We used fMRI to study the human imitation of hand/arm postures and finger configuration, subjects imitated hand/arm postures in the hand condition, and they imitated finger configurations in the finger condition. Compared with the control condition, only the finger condition showed significant activation in Broca's area and symmetrical activation in the(More)
We examined neural basis underlying tool-use behavior to discuss whether or not the usage of a well-learned tool has a specific route. Regional cerebral blood flow was measured in healthy Japanese subjects using functional magnetic resonance imaging (fMRI) during object pick-up using chopsticks, object pick-up using the hand, pantomiming the use of(More)
The present study investigated neural correlates of affect processing in allodynia patients (n=8) and healthy controls (n=12) with the aid of virtual tactile stimulation. Whole brain functional magnetic resonance imaging was performed for allodynia patients and healthy volunteers while they were shown a video demonstrating light stimulation of the palm and(More)
Psychological factors are known to play an extremely important role in the maintenance and development of chronic pain conditions. However, it is unclear how such factors relate to the central neural processing of nociceptive transmission in healthy individuals. To investigate this issue, the activation of the brain was studied in 30 healthy volunteers(More)
We describe a young woman who suddenly began mirror writing with her right hand and has not reverted to normal writing for more than 6 years, although she writes normally with her left hand. She is ambidextrous, although she had previously used only her right hand for writing and drawing. Since it is much easier for her to use right-handed mirror writing,(More)
In order to investigate how the brain represents sensory-specific information during memory retrieval, we examined functional magnetic resonance imaging's during a face-recognition task. When compared with activation associated with viewing of novel faces, recognition of faces presented 5 min before scanning activated the primary visual cortex, consistent(More)
An experimental study was conducted with a young woman who had suddenly developed mirror writing in the right hand, which she used for writing. She was not cured for eight years. The patient was ambidextrous and had no medical complaints except for migraine with perceptual and sensory abnormalities, and an enlarged cavity of the septum pellucidum. A(More)
—This article argues how dopamine controls working memory and how the dysregulation of the dopaminergic system is related to schizophrenia. In the dorsolateral pre-frontal cortex, which is the principal part of the working memory system, recurrent excitation is subtly balanced with intracortical inhibition. A potent controller of the dorsolateral prefrontal(More)
It is a frequent clinical observation that pain anxiety can exacerbate pain sensation. We compared the changes occurring in the brain of normal individuals and neuropathic pain patients with allodynia in response to virtual visual stimulation. At the time of taking brain fMRI, they were shown a video demonstrating painful stimulation of the palm and another(More)
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