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- Shinichiro Yamamoto, Shunichi Shimizu, +14 authors Yasuo Mori
- Nature Medicine
- 2008
Reactive oxygen species (ROS) induce chemokines responsible for the recruitment of inflammatory cells to sites of injury or infection. Here we show that the plasma membrane Ca2+-permeable channel… (More)
- Shigeki Kiyonaka, Kenta Kato, +19 authors Yasuo Mori
- Proceedings of the National Academy of Sciences…
- 2009
Canonical transient receptor potential (TRPC) channels control influxes of Ca(2+) and other cations that induce diverse cellular processes upon stimulation of plasma membrane receptors coupled to… (More)
- Hong-Shuo Sun, Michael F Jackson, +11 authors Michael Tymianski
- Nature Neuroscience
- 2009
Cardiac arrest victims may experience transient brain hypoperfusion leading to delayed death of hippocampal CA1 neurons and cognitive impairment. We prevented this in adult rats by inhibiting the… (More)
- Nobuaki Takahashi, Yusuke Mizuno, +5 authors Yasuo Mori
- Channels
- 2008
TRPA1 is a member of the transient receptor potential (TRP) cation channel family, and is predominantly expressed in nociceptive neurons of dorsal root ganglia (DRG) and trigeminal ganglia.… (More)
- Nobuaki Takahashi, Tomoyuki Kuwaki, +13 authors Yasuo Mori
- Nature chemical biology
- 2011
Oxygen (O(2)) is a prerequisite for cellular respiration in aerobic organisms but also elicits toxicity. To understand how animals cope with the ambivalent physiological nature of O(2), it is… (More)
- Yuichi Aiba, Masatsugu Oh-hora, +4 authors Tomohiro Kurosaki
- Proceedings of the National Academy of Sciences…
- 2004
The Ras signaling pathway plays a critical role in B lymphocyte development and activation, but its activation mechanism has not been well understood. At least one mode of Ras regulation in B cells… (More)
- Kenta Kato, Shigeki Kiyonaka, +9 authors Yasuo Mori
- Biochemistry
- 2009
Flubendiamide is a benzenedicarboxamide derivative that shows selective insecticidal activity against lepidopterous insects. The specific modulatory effects of flubendiamide on ryanodine binding in… (More)
- Yuusuke Maruyama, Toshihiko Ogura, +5 authors Chikara Sato
- The Journal of biological chemistry
- 2009
The Ca(2+) release-activated Ca(2+) channel is a principal regulator of intracellular Ca(2+) rise, which conducts various biological functions, including immune responses. This channel, involved in… (More)
- Michelle E. Olah, Michael F Jackson, +6 authors John F. Macdonald
- The Journal of physiology
- 2009
TRPM2 is a Ca(2+)-permeable member of the transient receptor potential melastatin family of cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and ADP-ribose (ADPR) is… (More)
- Yuusuke Maruyama, Toshihiko Ogura, +4 authors Chikara Sato
- The Journal of biological chemistry
- 2007
Transient receptor potential melastatin type 2 (TRPM2) is a redox-sensitive, calcium-permeable cation channel activated by various signals, such as adenosine diphosphate ribose (ADPR) acting on the… (More)