Shigeki Izumi

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This report presents, for the first time, comprehensive data on the incidence of solid cancer and risk estimates for A-bomb survivors in the extended Life Span Study (LSS-E85) cohort. Among 79,972 individuals, 8613 first primary solid cancers were diagnosed between 1958 and 1987. As part of the standard registration process of the Hiroshima and Nagasaki(More)
This paper presents an analysis of data on the incidence of leukemia, lymphoma and myeloma in the Life Span Study cohort of atomic bomb survivors during the period from late 1950 through the end of 1987 (93,696 survivors accounting for 2,778,000 person-years). These analyses add 9 additional years of follow-up for leukemia and 12 for myeloma to that in the(More)
We have examined whether parental exposure to atomic bomb radiation has led to increased cancer risks among the offspring. We studied 40 487 subjects born from May 1946 through December 1984 who were cancer-free in January 1958. One or both parents were in Hiroshima or Nagasaki at the time of the bombing and for childbirth. Using population-based tumor(More)
STUDY DESIGN Experimental laboratory study. OBJECTIVES To measure trunk muscle activity using wire electrodes during lumbar stabilization exercises and to examine if more effective exercises to activate the deep trunk muscles (local muscles) exist. BACKGROUND Lumbar stabilization exercises are performed to improve motor control of trunk muscles.(More)
STUDY DESIGN Controlled laboratory study. OBJECTIVES To clarify whether differences in surface stability influence trunk muscle activity. BACKGROUND Lumbar stabilization exercises on unstable surfaces are performed widely. One perceived advantage in performing stabilization exercises on unstable surfaces is the potential for increased muscular demand.(More)
Growth retardation due to exposure to the atomic bomb has been evaluated using repeated measurements of stature from 10 to 18 years of age. A highly significant growth retardation due to the DS86 uterine dose was observed in all trimesters combined and in the first and second trimesters of pregnancy. In the first trimester, all parameter estimates based on(More)
A variety of calcium phosphates have been used for bone tissue-engineering applications. We developed porous hydroxyapatite (HAp) ceramics by firing green compacts consisting of spherical carbon beads and HAp fiber. The apatite-fiber scaffold (AFS) forms a three-dimensional network of fibers with two different pore sizes (micro- and macropores). In this(More)
A method of fluorescent leprosy antibody absorption (FLA-ABS) test was described. This test was so sensitive that 81.8% of tuberculoid leprosy cases gave positive reaction even in early stage of the disease. More than 50% of indeterminate and contact cases were also positive in this test. The positive percentages as well as antibody-titers were increasing(More)
[Abstract] Purpose: The purpose of this study was to investigate the kinetics of cerebral blood flow (CBF) in conjunction with cardiopulmonary response during constant-work rate cycling exercise of moderate and heavy intensities. Methods: Seven subjects (6 males and 1 female; age, 25.4 ± 7.7 yr; height, 171.9 ± 4.3 cm; body mass, 67.7 ± 11.4 kg)(More)
Previous studies demonstrated that cerebral blood flow (CBF) changes during dynamic exercise and a physiological basis for this observation may be explained by the tight control of CBF by arterial carbon dioxide tension (PaCO2). This study examined whether the steady state of the middle cerebral artery blood flow velocity (MCAVmean) and PaCO2 could be(More)
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