Shie Lee Cheah

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BACKGROUND A previous individual patient data meta-analysis by the Meta-Analysis of Chemotherapy in Nasopharynx Carcinoma (MAC-NPC) collaborative group to assess the addition of chemotherapy to radiotherapy showed that it improves overall survival in nasopharyngeal carcinoma. This benefit was restricted to patients receiving concomitant chemotherapy and(More)
A case of congenital tracheobiliary fistula with absent common bile duct is reported. The patient presented with repeated aspiration pneumonia, and the diagnosis was established during bronchoscopy. Excision of the fistula and cholecystoduodenostomy were successful. This is the fourth reported case of its type and the first one to survive surgical(More)
PURPOSE To assess the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in patients with International Union Against Cancer (UICC)-staged III/IVA,B nasopharyngeal carcinoma (NPC), who were enrolled into two randomised controlled trials of concurrent/adjuvant chemotherapy when added to radiotherapy (SQNP01), and induction chemotherapy when added to(More)
BACKGROUND AND PURPOSE A planning margin ⩽3 mm is employed in some head-and-neck IMRT cases due to the proximity of critical structures. This study aims to explore the need to redefine the action-level in the head-and-neck imaging protocol in consideration of the intra-fraction movement. MATERIAL AND METHODS This is a local study of 18 patients treated(More)
Nasopharyngeal carcinoma (NPC) is a rare disease in the Western world, but it is endemic in certain parts of Southeast Asia and China. During the last decades, the outcome of the treatment has improved considerably. Concurrent chemo-radiation has become the treatment of choice in advanced NPC. Five years survival figures of 80-90 % for T1-T2 and 60-80 % for(More)
Quantification of Epstein-Barr virus (EBV) cell-free DNA (cfDNA) is commonly used in clinical settings as a circulating biomarker in nasopharyngeal carcinoma (NPC), but there has been no comparison with circulating tumour cells (CTCs). Our study aims to compare the performance of CTC enumeration against EBV cfDNA quantitation through digital PCR (dPCR) and(More)
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