Shichao Ma

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Tumor angiogenesis is a vital hallmark of cancer and a property of almost all types of solid tumors [1]. Tumors rely on blood vessels to acquire oxygen and nutrients for growth and for spreading to other organ. Consequently, cancer needs to induce angiogenesis, the process of neovascular blood accommodating [2-6]. As a consequence, structure-based drug(More)
Tripartite motif-containing 14 (TRIM14) is a mitochondrial adaptor that facilitates innate immune signaling. Upon virus infection, the expression of TRIM14 is significantly induced, which stimulates the production of type-I IFNs and proinflammatory cytokines. As excessive immune responses lead to harmful consequences, TRIM14-mediated signaling needs to be(More)
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