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Leptospiral Hemolysins Induce Proinflammatory Cytokines through Toll-Like Receptor 2-and 4-Mediated JNK and NF-κB Signaling Pathways
Background Infection with pathogenic Leptospira species causes serious systemic inflammation in patients. Although a few leptospiral proinflammatory molecules have been identified, Leptospira likelyExpand
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Epidemiology and risk factors of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci infections in Zhejiang China from 2015 to 2017
BackgroundGram-positive bacteria are dangerous and challenging agents of infection due to their increasing resistance to antibiotics. We aim to analyse the epidemiology and risk factors ofExpand
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Haemolysin Sph2 of Leptospira interrogans induces cell apoptosis via intracellular reactive oxygen species elevation and mitochondrial membrane injury
Leptospira interrogans causes widespread leptospirosis in humans and animals, with major symptoms of jaundice and haemorrhage. Sph2, a member of the sphingomyelinase haemolysins, is an importantExpand
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Modality of Leptospira interrogans invading mononuclear-macrophages and diversity of leptospiral phagocytotic vesicle formation
Objective To determine the modality of Leptospira interrogans invading human and murine mononuclear-macrophages and diversity of leptospiral phagocytotic vesicle formation. Methods TransmissionExpand
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Expression and characterization of recombinant L-amino acid deaminase of Proteus mirabilis isolated from acute pyelonephritis patients
To investigate function and enzymatic characteristics of L-amino acid deaminase of Proteus mirabilis from acute pyelonephritis patients, L-amino acid deaminase encoding genes (pmzd1 and pmzd2) wereExpand
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